Receptor - Based Drug Design - Couverture souple

 
9780367400521: Receptor - Based Drug Design
Couverture souple
ISBN 10 : 0367400529 ISBN 13 : 9780367400521
Editeur : CRC Press, 2019

Synopsis

Employing a wide range of examples from G-protein-coupled receptors and ligand-gated ion channels, this detailed, single-source reference illustrates the principles of pharmacological analysis and receptor classification that are the basis of rational drug design.
Explains the experimental and theoretical methods used to characterize interactions between ligands and receptors-providing the pharmacological information needed to solve treatment problems and facilitate the drug design process!
Demonstrating the achievements of the receptor-based approach in therapeutics and indicating future directions, Receptor-Based Drug Design

  • introduces novel computer-assisted strategies for the design of new agonists, antagonists, and inverse agonists for G-protein-coupled receptors
  • shows how to assess agonist concentration-effect curve data
  • discusses radioligand binding assays
  • presents new in vitro multiarray assays for G-protein-coupled receptors
  • explains the use of individual second messenger signaling responses in analyzing drug-receptor interactions
  • examines the role of electrophysiology in finding new drugs and drug targets
  • describes selectively acting b-adrenoceptor agonists and glucocorticoid steroids for asthma treatment
  • outlines the rationale for using angiotensin receptor antagonists
  • and more!
    Written by over 25 international authorities and containing nearly 1200 bibliographic citations, Receptor-Based Drug Design is a practical resource for pharmacologists, pharmacists, and pharmaceutical scientists; organic and medicinal chemists and biochemists; molecular biologists; biomedical researchers; and upper-level undergraduate and graduate students in these disciplines.

    • Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

    À propos de l?auteur

    Leff Paul

    Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

    Éditeur
    CRC Press
    Date d'édition
    2019
    Langue
    anglais
    ISBN 10 
    0367400529
    ISBN 13 
    9780367400521
    Reliure
    Broché
    Nombre de pages
    400
    Éditeur
    Leff Paul
    Coordonnées du fabricant
    non disponible
    Personne responsable
    gpsr@libri.de
    gpsr@libri.de

    Friedensallee 273
    Hamburg
    22763
    Allemagne

    Autres éditions populaires du même titre

    9781420001136: Receptor - Based Drug Design

    Edition présentée

    ISBN 10 :  1420001132 ISBN 13 :  9781420001136
    Couverture rigide