Predictive Analytics for Toxicology: Applications in Discovery Science - Couverture rigide

Valerio Jr., Luis G.

Couverture rigide

ISBN 10 : 0367775549 ISBN 13 : 9780367775544

Editeur : CRC Press, 2024

Synopsis

Predictive data science is already in use in many fields, but its application in toxicology is new and sought after by non-animal alternative testing initiatives. Predictive Analytics for Toxicology: Applications in Discovery Science provides a comprehensive overview of the application of predictive analytics in the field of toxicology, highlighting its role and applications in discovery science.

This book addresses the challenges of accurately predicting high-level endpoints of toxicity and explores the use of computational and artificial intelligence research to automate predictive toxicology. It underscores the importance of predictive toxicology in proposing and explaining adverse outcomes resulting from human exposures to specific toxicants, especially when experimental and observational data on the toxicant are incomplete or unavailable.

Key features:

• Includes a plain language description of predictive analytics in toxicology adding an overview of the wide range of applications
• Examines the science of prediction, computational models as an automated science and comprehensive discussions on concepts of machine learning
• Opens the hood on AI and its applications in toxicology
• Features coverage on how in silico toxicity predictions are translational science tools

The book integrates strategies and practices of predictive toxicology and offers practical information that students and professionals of the toxicology, chemical, and pharmaceutical industries will find essential. It fulfills the expectations of student researchers seeking to learn predictive analytics in toxicology. This book will energize scientists to conduct predictive toxicology modeling using artificial intelligence and machine learning, and inspire students and seasoned scientists interested in automated science to pick up new research using predictive in silico models to evaluate chemical-induced toxicity.

With its focus on practical applications and real-world examples, this book serves as a guide for navigating the complex issues and practices of discovery toxicology. It is an essential resource for those interested in computer-based methods in toxicology, providing valuable insights into the use of predictive analytics.

A propos du livre

À propos de l'auteur

Luis G. Valerio, Jr. has been a toxicologist for over 26 years. He has served in the public health arena for 20 years. He earned his Ph.D. in Pharmaceutical Science from the University of Colorado in Denver and is a board-certified toxicologist in the Academy of Toxicological Sciences. He was a National Research Council, National Academies of Sciences, Engineering, and Medicine Fellow in Gastroenterology at the University of Colorado, School of Medicine, Department of Medicine, Division of Gastroenterology and Hepatology. Following his academic research on the molecular regulation of cytochrome P450 1A1 and 1A2, he served as a National Science Foundation International Postdoctoral Research Fellow at the Autonomous University of Barcelona, Spain where he studied the biochemistry and metabolism of alcohol dehydrogenase enzymes. He served as a temporary advisor for the World Health Organization and on international scientific committees assessing the safety of chemicals added to food. He has worked on quality standards-setting committees for human pharmaceuticals. He has several years of industry experience in consumer product safety and chemical toxicology. He has overseen clinical studies to predict dermal hazards of consumer products. He has served as a Scientific Director of a food chemical and manufacturing trade association. He is currently Editor-in-Chief of the journals, Toxicology Mechanisms and Methods and Expert Opinion on Drug Metabolism & Toxicology (Taylor & Francis Group). He enjoys writing and has published 100 articles on a variety of topics in mechanisms of chemical toxicity, xenobiotic metabolism, safety science, and computational science.

À propos de la quatrième de couverture

This book addresses the challenges of accurately predicting high-level endpoints of toxicity and explores the use of computational and artificial intelligence research to automate predictive toxicology.

Détails de l'édition

• Éditeur: CRC Press
• Date d'édition: 2024
• Langue: anglais
• ISBN 10: 0367775549
• ISBN 13: 9780367775544
• Reliure: Relié
• Nombre de pages: 272
• Coordonnées du fabricant: non disponible
• Personne responsable: gpsr@libri.de; gpsr@libri.de; ; Europaallee 1; Bad Hersfeld; 36244; Allemagne