Bioinformatics of Genome Regulation and Structure II - Couverture rigide

 
9780387294506: Bioinformatics of Genome Regulation and Structure II

Synopsis

The last 15 years in development of biology were marked with accumulation of unprecedentedly huge arrays of experimental data. The information was amassed with exclusively high rates due to the advent of highly efficient experimental technologies that provided for high throughput genomic sequencing; of functional genomics technologies allowing investigation of expression dynamics of large groups of genes using expression DNA chips; of proteomics methods giving the possibility to analyze protein compositions of cells, tissues, and organs, assess the dynamics of the cell proteome, and reconstruct the networks of protein-protein interactions; and of metabolomics, in particular, high resolution mass spectrometry study of cell metabolites, and distribution of metabolic fluxes in the cells with a concurrent investigation of the dynamics of thousands metabolites in an individual cell. Analysis, comprehension, and use of the tremendous volumes of experimental data reflecting the intricate processes underlying the functioning of molecular genetic systems are unfeasible in principle without the systems approach and involvement of the state-of-the-art information and computer technologies and efficient mathematical methods for data analysis and simulation of biological systems and processes. The need in solving these problems initiated the birth of a new science-- postgenomic bioinformatics or systems biology in silico.

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Autres éditions populaires du même titre

9781461497707: Bioinformatics of Genome Regulation and Structure

Edition présentée

ISBN 10 :  1461497701 ISBN 13 :  9781461497707
Editeur : Birkhauser Boston Inc, 2014
Couverture souple