Principles of Clinical Cancer Genetics: A Handbook from the Massachusetts General Hospital - Couverture rigide

Couverture rigide

ISBN 10 : 0387938443 ISBN 13 : 9780387938448

Editeur : Springer-Verlag New York Inc., 2010

Synopsis

Advances in genetics are transforming estimates of an individual's risk of developing cancer and approaches to prevention and management of cancer in those who may have increased susceptibility. Identifying and caring for patients with hereditary cancer syndromes and their family members present a complex clinical, scientific and social challenge. This textbook, by leading experts at Massachusetts General Hospital Cancer Center, highlights the current understanding of the genetics of hereditary cancers of the breast, ovary, colorectum, stomach, pancreas, kidney, skin, and endocrine organs. Practical guidelines for the use of genetic testing, cancer screening and surveillance, prophylactic surgery, and promising targeted therapeutic agents are discussed.

In addition, ongoing research involving genome-wide screens to identify novel modest risk-associated genetic loci are explored, along with new approaches to the application of genetic markers in guiding therapeutic options.

A propos du livre

Présentation de l'éditeur

This text reviews current knowledge in the genetics of many hereditary cancers. It offers practical guidelines for the use of genetic testing, cancer screening and surveillance, and prophylactic surgery. It also discusses promising targeted therapeutic agents.

Détails de l'édition

• Éditeur: Springer-Verlag New York Inc.
• Date d'édition: 2010
• Langue: anglais
• ISBN 10: 0387938443
• ISBN 13: 9780387938448
• Reliure: Relié
• Nombre de pages: 238
• Éditeur: Chung Daniel C., Haber Daniel A.
• Coordonnées du fabricant: Springer Nature Customer Service Center GmbH; ProductSafety@springernature.com; ; Europaplatz 3; Heidelberg; 69115; Allemagne