Regulation of the Ras Signalling Network - Couverture rigide

Maruta, Hiroshi; Burgess, Antony

9780412118616: Regulation of the Ras Signalling Network

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ISBN 10 : 0412118610 ISBN 13 : 9780412118616

Editeur : Chapman and Hall, 1996

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This book, which was written by the current leaders in the field of Ras research, provides the readers with the most comprehensive and up-to-date w of the major oncogene Ras. This volume is valuable not only for university students in molear biology, biochemistry or medicine, but also for senior scientists currently conducting cancer research.

Les informations fournies dans la section � Synopsis � peuvent faire r�f�rence � une autre �dition de ce titre.

�diteur: Chapman and Hall
Date d'�dition: 1996
Langue: anglais
ISBN 10: 0412118610
ISBN 13: 9780412118616
Reliure: Reli�
Nombre de pages: 202
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Regulation of the RAS Signalling Network (Geophysics and Astrophysics Monographs, 6)

Maruta, Hiroshi,Burgess, Antony

Edit� par Springer, 1996

ISBN 10 : 0412118610 ISBN 13 : 9780412118616

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hardcover. Etat : Very Good. Bumps on corners*. N� de r�f. du vendeur mon0000670613

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Regulation of the RAS Signalling Network (Geophysics and Astrophysics Monographs, 6)

Maruta, Hiroshi; Burgess, Antony

Edit� par Springer, 1996

ISBN 10 : 0412118610 ISBN 13 : 9780412118616

Neuf Couverture rigide

Vendeur : Ria Christie Collections, Uxbridge, Royaume-Uni

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Regulation of the Ras Signalling Network

Hiroshi Maruta

Edit� par SPRINGER NATURE Nov 1996, 1996

ISBN 10 : 0412118610 ISBN 13 : 9780412118616

Neuf Couverture rigide

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Vendeur : BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Allemagne

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Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Inhaltsangabe1. Genetics of RAS Signaling in Drosophila.- I. Introduction.- II. Background to the Experimental Systems.- III. Protein Tyrosine Kinase Receptors.- IV. Linking RAS with Tyrosine Kinase Receptors.- V. A Kinase Cascade Downstream of RAS.- VI. Nuclear Events.- VII. Concluding Remarks.- 2. RAS-Mediated Signal Transduction in C. elegans.- I. Introduction.- II. Genetic Approaches Used to Study Vulval Signal Transduction.- III. Genetic and Molecular Analysis of the let-60 RAS Gene.- IV. Genes Acting Upstream of RAS.- V. Genes Acting Downstream of RAS.- VI. Multiple Functions of the let-60 RAS-mediated Signal Transduction Pathway During C elegans Development.- 3. Mammals I: Regulation of RAS Activation.- I. Introduction.- II. Growth Factor/Cytokine Signaling.- III. Growth Factor Cascades: Autocrine Stimulation.- 4. Prenylation of RAS and Inhibitors of Prenyltransferases.- I. Introduction.- II. C-Terminal Modification of RAS Proteins.- III. Farnesyltransferase and Geranylgeranyltransferases.- IV. Mutational Analyses of Prenyltransferases.- V. Inhibitors of Prenylation.- VI. Biological Effects of Prenyltransferase Inhibitors.- 5. Mammals II: Downstream of RAS and Actin-Cytoskeleton.- I. RAS GAPs.- II. Oncogenic Mutations of RAS.- III. Effectors of RAS.- IV. Actin-Cytoskeleton.- V. G Proteins in the Rho Family (Rho, Rac and CDC42).- VI. RAS-Activated or -Repressed Genes.- 6. From RAS to MAPK: Cell-Free Assay System for RAS- and Rap 1-Dependent B-Raf Activation.- I. Introduction.- II. Cell-free Assay System for the RAS-dependent Activation of the MAP Kinase Cascade in Xenopus Oocyte Cytosol.- III. REKS.- IV. Raf Activation.- V. Conclusion. 202 pp. Englisch. N� de r�f. du vendeur 9780412118616

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Regulation of the Ras Signalling Network

Hiroshi Maruta

Edit� par Springer Us, 1996

ISBN 10 : 0412118610 ISBN 13 : 9780412118616

Neuf Couverture rigide

Vendeur : AHA-BUCH GmbH, Einbeck, Allemagne

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Buch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - Inhaltsangabe1. Genetics of RAS Signaling in Drosophila.- I. Introduction.- II. Background to the Experimental Systems.- III. Protein Tyrosine Kinase Receptors.- IV. Linking RAS with Tyrosine Kinase Receptors.- V. A Kinase Cascade Downstream of RAS.- VI. Nuclear Events.- VII. Concluding Remarks.- 2. RAS-Mediated Signal Transduction in C. elegans.- I. Introduction.- II. Genetic Approaches Used to Study Vulval Signal Transduction.- III. Genetic and Molecular Analysis of the let-60 RAS Gene.- IV. Genes Acting Upstream of RAS.- V. Genes Acting Downstream of RAS.- VI. Multiple Functions of the let-60 RAS-mediated Signal Transduction Pathway During C elegans Development.- 3. Mammals I: Regulation of RAS Activation.- I. Introduction.- II. Growth Factor/Cytokine Signaling.- III. Growth Factor Cascades: Autocrine Stimulation.- 4. Prenylation of RAS and Inhibitors of Prenyltransferases.- I. Introduction.- II. C-Terminal Modification of RAS Proteins.- III. Farnesyltransferase and Geranylgeranyltransferases.- IV. Mutational Analyses of Prenyltransferases.- V. Inhibitors of Prenylation.- VI. Biological Effects of Prenyltransferase Inhibitors.- 5. Mammals II: Downstream of RAS and Actin-Cytoskeleton.- I. RAS GAPs.- II. Oncogenic Mutations of RAS.- III. Effectors of RAS.- IV. Actin-Cytoskeleton.- V. G Proteins in the Rho Family (Rho, Rac and CDC42).- VI. RAS-Activated or -Repressed Genes.- 6. From RAS to MAPK: Cell-Free Assay System for RAS- and Rap 1-Dependent B-Raf Activation.- I. Introduction.- II. Cell-free Assay System for the RAS-dependent Activation of the MAP Kinase Cascade in Xenopus Oocyte Cytosol.- III. REKS.- IV. Raf Activation.- V. Conclusion. N� de r�f. du vendeur 9780412118616

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Regulation of the Ras Signalling Network

Hiroshi Maruta|Antony Burgess

Edit� par Springer US, 1996

ISBN 10 : 0412118610 ISBN 13 : 9780412118616

Neuf Couverture rigide

Vendeur : moluna, Greven, Allemagne

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Gebunden. Etat : New. 1. Genetics of RAS Signaling in Drosophila.- I. Introduction.- II. Background to the Experimental Systems.- III. Protein Tyrosine Kinase Receptors.- IV. Linking RAS with Tyrosine Kinase Receptors.- V. A Kinase Cascade Downstream of RAS.- VI. Nuclear Events. N� de r�f. du vendeur 458434059

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