DNA Repair and Recombination - Couverture rigide

Couverture rigide

ISBN 10 : 0412640406 ISBN 13 : 9780412640407

Editeur : Chapman and Hall, 1995

Synopsis

Genomic instability is a major threat to living organisms. To counteract the damaging effects posed by endogenous and environmental agents, such as chemicals or radiation, micro-organisms devote several percent of their genome to encode proteins that function in the repair and recombination of DNA. For many years, a relatively small group of scientists have carefully delineated the molecular mechanisms of these repair processes, using the simplest model systems available, namely Escherichia coli and Saccharomyces cerevisiae. These studies, which until recently had only moderate impact outside of the field, now provide the cornerstone for exciting new research into analogous processes in human cells. The reason for this is the revelation that the biochemical pathways for the accurate replication, repair and recombination of DNA have been conserved through evolution.

Détails de l'édition

• Éditeur: Chapman and Hall
• Date d'édition: 1995
• Langue: anglais
• ISBN 10: 0412640406
• ISBN 13: 9780412640407
• Reliure: Relié
• Nombre de pages: 120
• Éditeur: Lindahl T., West S.C.
• Coordonnées du fabricant: Springer Nature Customer Service Center GmbH; ProductSafety@springernature.com; ; Europaplatz 3,69115 Heidelberg, Germany; Heidelberg; 69115; Allemagne