Articles liés à Dermal Absorption Models In Toxicology And Pharmacology

Dermal Absorption Models In Toxicology And Pharmacology - Couverture rigide

 
9780415700368: Dermal Absorption Models In Toxicology And Pharmacology
Couverture rigide
ISBN 10 : 0415700361 ISBN 13 : 9780415700368
Editeur : CRC Press, 2005

Synopsis

Many experimental methods and mathematical modeling approaches rooted in disciplines outside of toxicology can be effectively applied to estimating dermal absorption. Dermal Absorption Models in Toxicology and Pharmacology explores current approaches and techniques that can be used to quantify dermal absorption with endpoints useful in both toxicology and pharmacology.

The book begins with a review of basic principles and the in vitro and in vivo experimental approaches available for assessing dermal absorption of drugs and chemicals. This is followed by coverage of mathematical or in silico models for quantitating percutaneous absorption and the applications of these techniques to the risk assessment process. The remainder of the book explores scenarios where the unique properties of the chemicals being studied or the matrix in which they are exposed must be considered and then wraps up with a comparative analysis of chemical permeability in human and animal skin.

Many of the books covering this subject are just too comprehensive and serve primarily as reference works. This book takes a different approach. Jim Riviere's editorial guidance ensures that the information is readable, accessible, authoritative, and concise, making it the perfect resource for familiarizing new researchers and students to the field and updating established scientists.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Many experimental methods and mathematical modeling approaches rooted in disciplines outside of toxicology can be effectively applied to estimating dermal absorption. Dermal Absorption Models in Toxicology and Pharmacology explores current approaches and techniques that can be used to quantify dermal absorption with endpoints useful in both toxicology and pharmacology.

The book begins with a review of basic principles and the in vitro and in vivo experimental approaches available for assessing dermal absorption of drugs and chemicals. This is followed by coverage of mathematical or in silico models for quantitating percutaneous absorption and the applications of these techniques to the risk assessment process. The remainder of the book explores scenarios where the unique properties of the chemicals being studied or the matrix in which they are exposed must be considered and then wraps up with a comparative analysis of chemical permeability in human and animal skin.

Many of the books covering this subject are just too comprehensive and serve primarily as reference works. This book takes a different approach. Jim Riviere's editorial guidance ensures that the information is readable, accessible, authoritative, and concise, making it the perfect resource for familiarizing new researchers and students to the field and updating established scientists.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
CRC Press
Date d'édition
2005
Langue
anglais
ISBN 10 
0415700361
ISBN 13 
9780415700368
Reliure
Relié
Nombre de pages
374
Éditeur
Riviere J. Edmond
Coordonnées du fabricant
non disponible
Personne responsable
non disponible