The revised and reorganized second edition of this well-known and widely acclaimed reference on toxicology shows how to quickly determine the extent of the hazards posed by chemicals in the general environment and the workplace. The first six chapters provide an introduction to the nature of chemicals. There follows in-depth discussions of the routes of chemical exposure, differences in species, age, sex, health and nutrition as well as individual susceptibilities. All current toxicological issues are covered, including PCBs, Agent Orange, formaldehyde, and carcinogens. The second edition also features an expanded epidemiology section and the experimental and analytical methods are now organized in a single chapter. Moreover, important topical issues such as risk and the public distrust of science are addressed. This book should be of interest to environmental engineers; hazardous material managers and legal personnel dealing with tort.
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The Dose Makes the Poison A Plain–Language Guide to Toxicology Second Edition M. Alice Ottoboni Increasing media coverage of reports on the effects of chemicals, new recognition within government and industry of the need to protect against exposure, and other current issues are elevating the public’s concern about the health effects of synthetic chemicals in our environment. Unfortunately, much of this concern is based more on sensational news reports and half–truths than on scientific facts. This second edition of a widely read and highly acclaimed work reviews and explains the facts of chemical dangers in a clear and understandable manner. It objectively discusses the factors determining whether chemicals in our air, food, and water are harmful or harmless, and puts the dose – response relationship of chemicals in proper perspective. Effects of chemicals encountered at home and at work are presented in layman’s language to assure understanding without having to turn to other references. Thoughtful discussions of controversial issues help you to understand news media reports on toxicology, avoid the half–truths that lead to "poison paranoia," and make informed judgments about our use and control of chemicals. Extensively revised, the second edition is also reorganized to expedite access to specific information. All experimental and analytical methods are in one section, and references to the origins of toxicology and regulation of chemicals are in another separate section to improve ease of reading. In addition, coverage of subjects such as public distrust of science, epidemiology, reproductive toxicology, and risk have been expanded to provide a better understanding of the relationship of toxicology to current environmental problems. All aspects of exposure and its effects are reviewed, including
"This is a refreshing, invigorating as well as eye–opening text, which is reading like an exciting novel – even to a seasoned toxicologist ... An appendix to clarify quantities of pollutants plus an index concludes this most valuable introduction into the science of toxicology for a broad readership." (Toxicology, 2011)
"I recommend this book to anyone who has ever listened to the evening news and wondered how much of the "chemical scare du jour" is hype and how much of it is fact – and to those who might want to understand basic concepts in toxicology and the related areas of study without having to trudge through a gaggle of 1000–page textbooks." (International Journal of Toxicology, 2011)
"Overall, this is a well–written work with wisely chosen and relevant topics. It will be a perfect addition to any science enthusiast′s library. Summing Up: Highly recommended. Lower–level undergraduates through professionals/practitioners; general readers." (Choice, 1 September 2011)
"The Dose Makes the Poison is more than just an introduction to toxicology. It is an enjoyable read with lots of interesting stories and one I can thoroughly recommend." (Chemistry & Industry, 25 July 2011)
"There is much to be applauded in this book from its straightforward layout and honesty to its accessibility . . . Many good, and contemporary, examples are provided to deliver greater context for the reader." (The British Toxicology Society Journal, 1 May 2011)
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