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The Dose Makes the Poison - Couverture souple

 
9780442025564: The Dose Makes the Poison

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The Dose Makes the Poison A Plain–Language Guide to Toxicology Second Edition M. Alice Ottoboni Increasing media coverage of reports on the effects of chemicals, new recognition within government and industry of the need to protect against exposure, and other current issues are elevating the public’s concern about the health effects of synthetic chemicals in our environment. Unfortunately, much of this concern is based more on sensational news reports and half–truths than on scientific facts. This second edition of a widely read and highly acclaimed work reviews and explains the facts of chemical dangers in a clear and understandable manner. It objectively discusses the factors determining whether chemicals in our air, food, and water are harmful or harmless, and puts the dose – response relationship of chemicals in proper perspective. Effects of chemicals encountered at home and at work are presented in layman’s language to assure understanding without having to turn to other references. Thoughtful discussions of controversial issues help you to understand news media reports on toxicology, avoid the half–truths that lead to "poison paranoia," and make informed judgments about our use and control of chemicals. Extensively revised, the second edition is also reorganized to expedite access to specific information. All experimental and analytical methods are in one section, and references to the origins of toxicology and regulation of chemicals are in another separate section to improve ease of reading. In addition, coverage of subjects such as public distrust of science, epidemiology, reproductive toxicology, and risk have been expanded to provide a better understanding of the relationship of toxicology to current environmental problems. All aspects of exposure and its effects are reviewed, including

  • How chemicals cause harm toxicity, sensitization, corrosiveness, irritation, radioactivity, and other properties
  • Routes of exposure skin, inhalation, oral, and combinations
  • Factors that influence degree of toxicity species, age, sex, nutrition, state of health, presence of other chemicals, adaptation, and possibly, light
  • Chemicals that cause cancer and birth defects
Chapters on toxicity of chemicals address no–effect levels and thresholds, margins of safety, and bioaccumulation. You’ll see how the effects of chemicals are studied and how health problems are traced to environmental causes. Also clarified are differences between actual risk and perceived risk of various chemicals. With the media presenting us daily with new findings on chemical risks, this book provides a welcome "antidote" to the confusion. The Dose Makes the Poison is an easy–to–read review of toxicology that has become "required reading" for scientists and managers throughout industry; public health officials; environmental scientists; industrial hygienists; hazardous waste workers ; and anyone who wishes to improve his or her understanding of toxic chemicals without taking the time to go back to school.

Revue de presse

"This is a refreshing, invigorating as well as eye–opening text, which is reading like an exciting novel – even to a seasoned toxicologist ... An appendix to clarify quantities of pollutants plus an index concludes this most valuable introduction into the science of toxicology for a broad readership." (Toxicology, 2011)

"I recommend this book to anyone who has ever listened to the evening news and wondered how much of the "chemical scare du jour" is hype and how much of it is fact – and to those who might want to understand basic concepts in toxicology and the related areas of study without having to trudge through a gaggle of 1000–page textbooks." (International Journal of Toxicology, 2011)

"Overall, this is a well–written work with wisely chosen and relevant topics. It will be a perfect addition to any science enthusiast′s library. Summing Up: Highly recommended. Lower–level undergraduates through professionals/practitioners; general readers." (Choice, 1 September 2011)

"The Dose Makes the Poison is more than just an introduction to toxicology. It is an enjoyable read with lots of interesting stories and one I can thoroughly recommend." (Chemistry & Industry, 25 July 2011)

"There is much to be applauded in this book from its straightforward layout and honesty to its accessibility . . . Many good, and contemporary, examples are provided to deliver greater context for the reader." (The British Toxicology Society Journal, 1 May 2011) 

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