Ayurvedic Herbal Preparations in Neurological Disorders provides a comprehensive and mechanistic understanding of the therapeutic potential of many ayurvedic herbal preparations in disease management. Examining research data for evidence-based ayurvedic approaches, this volume begins with a focused introduction to major ayurvedic plants, discussing various mechanisms underlying their neuromodulatory potential in preclinical and clinical settings. Major subsets of ayurvedic plants are discussed, including Bacopa monnieri, Centella asiatica, Withania somnifera, and others. This volume outlines the importance of integrative approaches along with existing treatments in the intervention/management of Alzheimer's disease, Parkinson's disease, depressive mood disorders, epilepsy, schizophrenia, and more.
More than a mere compilation of studies, this volume identifies relevant gaps for future research avenues and encourages interdisciplinary collaboration and sharing of knowledge to together identify the most efficacious ayurvedic approaches. Highlighting recent developments (e.g., Ayurgenomics, Ayurahar) and other pertinent research for neuroprotection, this book is crucial for anyone researching or working in the field of neurological disorder treatment and prevention.
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Dr. Muralidhara is Chief Scientist and former Head of the Department of Biochemistry and Nutrition at CSIR (Central Food Technological Research Institute). Having mentored 15 Doctoral candidates and 25 Master's students, he has published 12 book chapters and 96 papers in peer-reviewed journals. A toxicologist by training, he has extensive research experience in the area of neurotoxicology with special reference to the neuromodulatory effects of Ayurvedic herbal plants, spice active principles, and nutraceuticals in cell models, Drosophila, and rodent models to understand underlyin molecular, biochemical, and oxidative stress mechanisms. He has worked primarily with three Ayurvedic plants (Bacopa monneri, Centella asiatica and Withania sominfera) in various preclinical models. His research has also looked at the modulatory potential of selected Ayurvedic herbal plants under experimentally induced hyperglycemic state in pregnant rats, and the protective effects of pro/prebiotics against toxicant-induced neuropathological conditions
Dr. Rajini is Senior Principal Scientist at CSIR (Central Food Technological Research Institute). She has pioneered in the area of pesticide toxicology, amelioration of toxicity by dietary components, and developed small animal models (C. elegans and Drosophila) for studying mechanistic toxicology. Her research focus has been the identification of novel food/plant-based components for prophylactic and ameliorative strategies to combat xenobiotic toxicity and ensuing disease progression. Her studies have addressed causes and probable mitigation of hyperglycemia, neurological disorders (Parkinson's disease in particular), hypertension, and gastrointestinal disorders. Dr. Rajini has mentored 14 Doctoral candidates and 15 Master's students and has published 5 book chapters and 64 papers in peer reviewed journals.
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