Structural and Evolutionary Genomics: Natural Selection in Genome Evolution - Couverture rigide

Bernardi, Giorgio

 
9780444512550: Structural and Evolutionary Genomics: Natural Selection in Genome Evolution
Couverture rigide
ISBN 10 : 0444512551 ISBN 13 : 9780444512550
Editeur : Elsevier Science Ltd, 2004

Synopsis

Structural genomics is the study of the DNA of living organisms. Evolutionary genomics is the study of the history of the genome. These subjects are closely interlinked. They are approached in this book using as a guideline the investigations carried out in the author's laboratory, relevant literature is critically reviewed and some general conclusions are presented. The author and his collaborators have studied a vast number of genomes, ranging from prokaryotes to human, using different approaches, including physical chemistry of DNA, viral integration and molecular cytogenetics. As the subtitle indicates the book discusses the fundamental importance of natural selection in shaping genomes. In terms of numbers, neutral and nearly neutral mutations represent most mutations, but a regional control is exerted by natural selection (essentially negative or purifying selection). A neo-selectionist model is proposed for genome evolution.

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Éditeur
Elsevier Science Ltd
Date d'édition
2004
Langue
anglais
ISBN 10 
0444512551
ISBN 13 
9780444512550
Reliure
Relié
Nombre de pages
342
Coordonnées du fabricant
non disponible
Personne responsable
Barbara Criscuolo
b.criscuolo@lswr.it

Via Spadolini, 7
Milano
20141
Italie