Endocrine Manifestations of Systemic Autoimmune Diseases - Couverture souple

Couverture souple

ISBN 10 : 0444603158 ISBN 13 : 9780444603159

Editeur : Elsevier Science, 2014

Synopsis

This book is one of the first to evaluate the role of Steroids in autoimmune rheumatic diseases from the basic mechanisms to the clinical involvements and focuses on the importance of steroidal hormones in the pathogenesis and therapeutic management of the autoimmune rheumatic diseases. In particular, the chapters analyze the mechanisms of action and the involvement of adrenal steroids (glucocorticoids) in the neuroendocrine immune system, including effects on the elderly. The perturbations of the HPA axis as a source of altered steroidal synthesis will be discussed and related to some interesting pathological conditions that commonly complicate the autoimmune rheumatic diseases such as psychosis or fibromyalgia. Concerning the role of gonadal steroids (sex hormones), several chapters will discuss clinical and epidemiological evidences of their role, as well as their effects as risk factors in autoimmune rheumatic diseases, including a section on pediatrics.

Détails de l'édition

• Éditeur: Elsevier Science
• Date d'édition: 2014
• Langue: anglais
• ISBN 10: 0444603158
• ISBN 13: 9780444603159
• Reliure: Broché
• Nombre de pages: 352
• Éditeur: Asherson Ronald
• Coordonnées du fabricant: non disponible
• Personne responsable: Barbara Criscuolo; b.criscuolo@lswr.it; ; Via Spadolini, 7; Milano; 20141; Italie