Reports of symptomatic drug-induced hepatic injury generally concern idiosyncratic reactions experienced during drug treatment, and these tend to be published at random all over the world, often in secondary journals and inaccessible languages. In contrast, the large and well-designed clinical trials of new drugs, performed in clinical centres of high reputation, find their way into the leading medical journals. The authors of this volume have now collected all the information available from both `streams' and to this they have added, where necessary, unpublished data if this is well documented. The result is this most comprehensive review of all reports of adverse drug reactions affecting the liver. The 4,000 journals screened for the Excerpta Medica database have provided the back-up for the volume. This uniquely complete volume provides essential reading for everyone concerned with drug prescribing, research and regulation.
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