Signalling Networks In Cell Shape And Motility - Couverture rigide

Couverture rigide

ISBN 10 : 0470011904 ISBN 13 : 9780470011904

Editeur : John Wiley & Sons Inc, 2005

Synopsis

This book features contributions from experts in cell biology, genetics, neurobiology, immunology and structural biology. The unifying element is that they all study processes of cell shape change and motility. Several key questions in this field of research are discussed:

• What are the organising principles behind cell shape change?
• Are there 'master switches' present in every cell type?
• How are extracellular signals interpreted by the cell in order to activate intracellular mechanisms?
• What is the influence of the extracellular matrix on cell movement and internal signalling pathways?
• How do pathogens subvert cellular systems in order to stimulate or block their uptake?

The book addresses all of these important questions. Data are presented on the key proteins that regulate cell shape: the GTP binding proteins of the Rho family. There are also extensive discussions of the potential applications of the data to clinical problems, particularly that of cell motility in cancer.

A propos du livre

À propos de l?auteur

The Novartis Foundation is an international scientific and educational charity which promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research.

Détails de l'édition

• Éditeur: John Wiley & Sons Inc
• Date d'édition: 2005
• Langue: anglais
• ISBN 10: 0470011904
• ISBN 13: 9780470011904
• Reliure: Relié
• Nombre de pages: 256
• Éditeur: Bock Gregory R., Goode Jamie A.
• Coordonnées du fabricant: non disponible
• Personne responsable: non disponible