Decoding the Genomic Control of Immune Reactions (281) - Couverture rigide

 
9780470027554: Decoding the Genomic Control of Immune Reactions (281)
Couverture rigide
ISBN 10 : 047002755X ISBN 13 : 9780470027554
Editeur : John Wiley & Sons Inc, 2007

Synopsis

This book explores existing and potential strategies for using the genome sequences of human, mouse, other vertebrates and human pathogens to solve key problems in the treatment of immunological diseases and chronic infections.  The assembled genome sequences now provide important opportunities for solving these problems, but a major bottleneck is the identification of key sequences and circuits controlling the relevant immune reactions. This will require innovative, interdisciplinary and collaborative strategies of a scale and complexity we are only now beginning to comprehend.

Specific problems addressed include the following:

  • What kinds of information are we lacking to understand how the genome sequence specifies the differentiation and response of immune system cells, and system behaviour such as immunological memory and tolerance?
  • Which genome sequences and cellular circuits cause or prevent pathological immune responses to foreign pathogens, allergens or self-tissues?
  • Which host and pathogen genome sequences and cellular circuits explain the failure of sterilizing immune responses to sophisticated human pathogens such as the agents of tuberculosis, malaria, metazoan parasites and chronic viruses?

Containing contributions from a range of leading experts in the field, this book provides an important new perspective for clinical immunologists and basic researchers alike.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

À propos de l?auteur

The Novartis Foundation is an international scientific and educational charity which promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
John Wiley & Sons Inc
Date d'édition
2007
Langue
anglais
ISBN 10 
047002755X
ISBN 13 
9780470027554
Reliure
Relié
Nombre de pages
232
Éditeur
Bock Gregory R., Goode Jamie A.
Coordonnées du fabricant
non disponible
Personne responsable
non disponible

Autres éditions populaires du même titre

9780470062128: Decoding the Genomic Control of Immune Reactions: Novartis Foundation Sympo

Edition présentée

ISBN 10 :  0470062126 ISBN 13 :  9780470062128
Editeur : John Wiley & Sons, 2007
Couverture souple