Acetaldehyde-Related Pathology: Bridging the Trans-disciplinary Divide - Couverture rigide

Couverture rigide

ISBN 10 : 0470057661 ISBN 13 : 9780470057667

Editeur : John Wiley & Sons Inc, 2007

Synopsis

Part of the prestigious Novartis Foundation, this is the first book to review the pathology associated with acetaldehyde, a known toxic agent found in cigarette smoke and other pollutants and derived from ingested alcohol, amongst other sources. In the body, acetaldehyde affects several tissues, particularly the brain and liver, causing various diseases, including cancer, alcoholic liver disease and Alzheimer's.

Acetaldehyde-Related Pathology describes the toxic effects of acetaldehyde at the tissue and cellular levels, reviewing enzyme biochemistry, transgenic mouse models of alcohol dehydrogenase mutants, and the cell-signalling pathways implicated in alcohol-related pathology. It explores the mechanisms of acetaldehyde-induced damage to tissues, often a first step in carcinogenesis, including the oral cavity, the human airway, and the GI tract. The book considers pharmacological strategies and treatments for reducing oral and intestinal acetaldehyde. Acetaldehyde-Related Pathology features in-depth, round-table discussions by an international array of scientists from major laboratories worldwide involved in studies of acetaldehyde-related pathology.

This book is essential reading for anyone interested in the effects of this compound - pathologists, biochemists, toxicologists, cell and molecular biologists.

A propos du livre

À propos de l?auteur

The Novartis Foundation is an international scientific and educational charity which promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research.
Chairman: Peter Emery

Détails de l'édition

• Éditeur: John Wiley & Sons Inc
• Date d'édition: 2007
• Langue: anglais
• ISBN 10: 0470057661
• ISBN 13: 9780470057667
• Reliure: Relié
• Nombre de pages: 286
• Éditeur: Chadwick Derek J., Goode Jamie A.
• Coordonnées du fabricant: non disponible
• Personne responsable: non disponible