The Agile Approach to Adaptive Research: Optimizing Efficiency in Clinical Development - Couverture rigide

Rosenberg, Michael J.

 
9780470247518: The Agile Approach to Adaptive Research: Optimizing Efficiency in Clinical Development
Couverture rigide
ISBN 10 : 0470247517 ISBN 13 : 9780470247518
Editeur : John Wiley & Sons Inc, 2010

Synopsis

Apply adaptive research to improve results in drug development

The pharmaceutical industry today faces a deepening crisis: inefficiency in its core business, the development of new drugs. The Agile Approach to Adaptive Research offers a solution. It outlines how adaptive research, using already-available tools and techniques, can enable the industry to streamline clinical trials and reach decision points faster and more efficiently.

With a wealth of real-world cases and examples, author Michael Rosenberg gives readers a practical overview of drug development, the problems inherent in current practices, and the advantages of adaptive research technology and methods. He explains the concepts, principles, and specific techniques of adaptive research, and demonstrates why it is an essential evolutionary step toward improving drug research and development.

Chapters explore such subjects as:

  • The adaptive concept

  • Design and operational adaptations

  • Sample-size reestimation

  • Agile clinical development

  • Safety and dose finding

  • Statistics in adaptive research, including frequentist and Bayesian approaches

  • Data management technologies

  • The future of clinical development

By combining centuries-old intellectual foundations, recent technological advances, and modern management techniques, adaptive research preserves the integrity and validity of clinical research but dramatically improves efficiency.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

À propos de l?auteur

MICHAEL J. ROSENBERG, MD, MPH, is President and Chief Executive Officer of Health Decisions, Inc. Involved in the design and execution of pharmaceutical development programs for more than twenty-five years, Dr. Rosenberg was selected as Entrepreneur of the Year by Ernst & Young (Health Sector, SE). His company's innovative applications of technology have been recognized by the CIO Enterprise Value Award and the Cisco Growing with Technology Award. Health Decisions has also been named three times to the Deloitte & Touche Technology Fast 500 and the Inc. 500. Dr. Rosenberg is the author of more than 150 scientific articles and serves on advisory groups in business, technology, and medicine.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
John Wiley & Sons Inc
Date d'édition
2010
Langue
anglais
ISBN 10 
0470247517
ISBN 13 
9780470247518
Reliure
Relié
Numéro d'édition
1
Nombre de pages
304
Coordonnées du fabricant
non disponible
Personne responsable
non disponible