This reference book originates from the interdisciplinary research cooperation between academia and industry. In three distinct parts, latest results from basic research on stable enzymes are explained and brought into context with possible industrial applications. Downstream processing technology as well as biocatalytic and biotechnological production processes from global players display the enormous potential of biocatalysts. Application of "extreme" reaction conditions (i.e. unconventional, such as high temperature, pressure, and pH value) - biocatalysts are normally used within a well defined process window - leads to novel synthetic effects. Both novel enzyme systems and the synthetic routes in which they can be applied are made accessible to the reader. In addition, the complementary innovative process technology under unconventional conditions is highlighted by latest examples from biotech industry.
Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.
John Whittall
CoEBio3, Manchester Interdisciplinary Biocentre, Manchester University, UK
Peter W Sutton
GlaxoSmithKline Research and Development Limited, UK
Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.
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Etat : Sehr gut. Zustand: Sehr gut | Seiten: 432 | Sprache: Englisch | Produktart: Bücher | Biocatalysts are increasingly used by chemists engaged in fine chemical synthesis within both industry and academia. Today, there exists a huge choice of high-tech enzymes and whole cell biocatalysts, which add enormously to the repertoire of synthetic possibilities. Practical Methods for Biocatalysis and Biotransformations is a "how-to" guide focussing on commercially available enzymes and strains of microorganisms that are readily obtained from culture collections. The source of starting materials and reagents, hints, tips and safety advice (where appropriate) are given to ensure, as far as possible, that the procedures are reproducible. Comparisons to alternative methodology are given and relevant references to the primary literature are cited. Contents include: Introduction to the application of biocatalysts in the pharma industry introduction to molecular biological techniques for biocatalyst development Lipase and protease methods including enzyme supports and dynamic kinetic resolutions Nitrile hydrolases and hydratases Alcohol dehydrogenases and co-factor recycling Epoxide hydrolases Amino acid synthesis Whole cell processes Other biocatalysts, including monoamineoxidases, aminotransterases, and lyases Practical Methods for Biocatalysis and Biotransformations is an essential text offering validated biocatalyst methods for researchers and postgraduate students in industry and academia. N° de réf. du vendeur 6003998/202
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