Essentials of Pharmaceutical Preformulation - Couverture souple

Gaisford, Simon; Saunders, Mark

Couverture souple

ISBN 10 : 0470976365 ISBN 13 : 9780470976364

Editeur : Blackwell Pub, 2013

Synopsis

Essentials of Pharmaceutical Preformulation is a study guide which describes the basic principles of pharmaceutical physicochemical characterisation. Successful preformulation requires knowledge of fundamental molecular concepts (solubility, ionisation, partitioning, hygroscopicity and stability) and macroscopic properties (physical form, such as the crystalline and amorphous states, hydrates, solvates and co-crystals and powder properties), familiarity with the techniques used to measure them and appreciation of their effect on product performance, recognising that often there is a position of compromise to be reached between product stability and bioavailability.This text introduces the basic concepts and discusses their wider implication for pharmaceutical development, with reference to many case examples of current drugs and drug products. Special attention is given to the principles and best-practice of the analytical techniques that underpin preformulation (UV spectrophotometry, TLC, DSC, XRPD and HPLC). The material is presented in the typical order that would be followed when developing a medicine and maps onto the indicative pharmacy syllabus of the Royal Pharmaceutical Society of Great BritainUndergraduate-level pharmacy students and R&D / analytical scientists working in the pharmaceutical sector (with or without a pharmaceutical background) will find this text easy to follow with relevant pharmaceutical examples.Essential study guide for pharmacy and pharmaceutical science studentsCovers the pharmaceutical preformulation components of the Royal Pharmaceutical Society of Great Britain?s indicative syllabusEasy to follow text highlighted with relevant pharmaceutical examplesSelf-assessment assignments in a variety of formatsWritten by authors with both academic and industrial experienceCompanion website with further information to maximise learning

A propos du livre

Présentation de l'éditeur

Essentials of Pharmaceutical Preformulation is a studyguide which describes the basic principles of pharmaceuticalphysicochemical characterisation. Successful preformulationrequires knowledge of fundamental molecular concepts (solubility,ionisation, partitioning, hygroscopicity and stability) andmacroscopic properties (physical form, such as the crystalline andamorphous states, hydrates, solvates and co–crystals and powderproperties), familiarity with the techniques used to measure themand appreciation of their effect on product performance,recognising that often there is a position of compromise to bereached between product stability and bioavailability.

This text introduces the basic concepts and discusses theirwider implication for pharmaceutical development, with reference tomany case examples of current drugs and drug products. Specialattention is given to the principles and best–practice of theanalytical techniques that underpin preformulation (UVspectrophotometry, TLC, DSC, XRPD and HPLC). The material ispresented in the typical order that would be followed whendeveloping a medicine and maps onto the indicative pharmacysyllabus of the Royal Pharmaceutical Society of Great Britain

Undergraduate–level pharmacy students and R&D / analyticalscientists working in the pharmaceutical sector (with or without apharmaceutical background) will find this text easy to follow withrelevant pharmaceutical examples.

• Essential study guide for pharmacy and pharmaceutical sciencestudents
• Covers the pharmaceutical preformulation components of theRoyal Pharmaceutical Society of Great Britain s indicativesyllabus
• Easy to follow text highlighted with relevant pharmaceuticalexamples
• Self–assessment assignments in a variety of formats
• Written by authors with both academic and industrialexperience
• Companion website with further information to maximiselearning

Détails de l'édition

• Éditeur: Blackwell Pub
• Date d'édition: 2013
• Langue: anglais
• ISBN 10: 0470976365
• ISBN 13: 9780470976364
• Reliure: Broché
• Numéro d'édition: 1
• Nombre de pages: 252
• Coordonnées du fabricant: Wiley-Blackwell; https://www.wiley.com/en-in; ; Via Bruno Buozzi, 24/26,; Granarolo dell'Emilia BO,; 40057; Italie