Apoptosis and the Immune Response - Couverture rigide

Couverture rigide

ISBN 10 : 0471012513 ISBN 13 : 9780471012511

Editeur : Wiley-Liss Inc.,U.S., 1995

Synopsis

Apoptosis and the Immune Response

Edited by Christopher D. Gregory

In this timely and important work, an international group ofleading investigators takes a close and critical look at programmedcell death and its role in the development, function, andmaintenance of the immune system. Along with covering the primaryactions of apoptosis, the contributors probe its role incarcinogenesis and HIV-induced pathogenesis. By offering a broadrange of views, Apoptosis and the Immune Response presents acurrent and complete picture of the various aspects andconsequences of this phenomenon.

Apoptosis and the Immune Response begins with the theoriessurrounding apoptosis and then covers its basic mechanismsincluding the morphologic, biochemical, and genetic features. Thebook offers authoritative discussions on the role of apoptosis inthe deletion of self-reactive lymphocytes, prevention ofautoimmunity, termination of the immune response, death of T cellsinfected by the HIV virus, neoplasia, and the homeostaticregulation of the hematopoietic system.

In particular, this excellent reference critiques such topics as:
* Apoptosis in thymocytes in vivo and in vitro
* Bcl-2/T-cell transgenics
* The role of c-myc
* Fas/APO-1 antigens and their roles
* Transgenic models of B-cell tolerance and autoimmunity
* How apoptosis affects the pathogenesis of AIDS and theimplications for therapy
* Triggers for apoptosis and survival
* Recognition of apoptotic cells by phagocytes
* Apoptosis in peritoneal autoreactive CD5+ B cells
* and more

With its diverse expertise and timely, clear-cut insights, Apoptosis and the Immune Response will prove to be an invaluableresource for immunologists, cell and developmental biologists, hematologists, and oncologists--as well as graduate students.

Cover Design: Janice Noto-Helmers

A propos du livre

À propos de l'auteur

Christopher D. Gregory is the author of Apoptosis and the Immune System, published by Wiley.

Détails de l'édition

• Éditeur: Wiley-Liss Inc.,U.S.
• Date d'édition: 1995
• Langue: anglais
• ISBN 10: 0471012513
• ISBN 13: 9780471012511
• Reliure: Relié
• Nombre de pages: 432
• Éditeur: Gregory Christopher D.
• Coordonnées du fabricant: Wiley VCH Verlag GmbH; info@wiley-vch.de; ; Boschstraße 12; Weinheim; Baden-Württemberg; 69469; Allemagne