Articles liés à Stroke Therapy: Basic, Preclinical, and Clinical Directions

Stroke Therapy: Basic, Preclinical, and Clinical Directions - Couverture rigide

 
9780471183471: Stroke Therapy: Basic, Preclinical, and Clinical Directions
Couverture rigide
ISBN 10 : 0471183474 ISBN 13 : 9780471183471
Editeur : John Wiley & Sons Inc, 1999

Synopsis

Basic scientists and clinicians alike will find Stroke Therapy fascinating and informative reading. Featuring contributions from leading North American and European researchers, it is the only book covering ongoing developments in the entire breadth of the contemporary stroke therapeutic landscape-from bench to bedside. Stroke Therapy begins with an overview of the basic mechanisms and relevant animal models for studying the neuropathology of stroke, both within brain parenchyma and at the cerebrovascular level. This material is followed by an in-depth look at the ischemic cascade in light of current drug development efforts aimed at intervening at specific steps along the cascade. The final section of the book is devoted to past, present, and future directions in the development of drug therapies for stroke. Chapters explore promising drug therapies now in clinical trials, as well as key design considerations involved in developing reliable tests for the clinical effectiveness of compounds proven effective in preclinical testing. The only book covering developments in all basic and clinical aspects of pharmacological therapies for ischemic brain injury, Stroke Therapy examines important recent findings on: The ischemic cascade and the neuropathological consequences of stroke The latest findings on the role of cell surface receptors and channels, nitric oxide and free radicals, and various intracellular processes in stroke, including DNA damage and repair Reparative approaches, including growth factors Clinical aspects from trial design and in incidents of perioperative CNS dysfunction, to thrombolytic and current mechanism-based drug therapies. Stroke Therapy is a valuable working resource for scientists in academe and industry, clinical investigators, and technical managers of pharmaceutical companies involved in stroke-related research.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Basic scientists and clinicians alike will find Stroke Therapy fascinating and informative reading. Featuring contributions from leading North American and European researchers, it is the only book covering ongoing developments in the entire breadth of the contemporary stroke therapeutic landscape–from bench to bedside.

Stroke Therapy begins with an overview of the basic mechanisms and relevant animal models for studying the neuropathology of stroke, both within brain parenchyma and at the cerebrovascular level. This material is followed by an in–depth look at the ischemic cascade in light of current drug development efforts aimed at intervening at specific steps along the cascade. The final section of the book is devoted to past, present, and future directions in the development of drug therapies for stroke. Chapters explore promising drug therapies now in clinical trials, as well as key design considerations involved in developing reliable tests for the clinical effectiveness of compounds proven effective in preclinical testing.

The only book covering developments in all basic and clinical aspects of pharmacological therapies for ischemic brain injury, Stroke Therapy examines important recent findings on:
∗ The ischemic cascade and the neuropathological consequences of stroke
∗ The latest findings on the role of cell surface receptors and channels, nitric oxide and free radicals, and various intracellular processes in stroke, including DNA damage and repair
∗ Reparative approaches, including growth factors
∗ Clinical aspects from trial design and in incidents of perioperative CNS dysfunction, to thrombolytic and current mechanism–based drug therapies.

Stroke Therapy is a valuable working resource for scientists in academe and industry, clinical investigators, and technical managers of pharmaceutical companies involved in stroke–related research.

Revue de presse

"For those with competence in the area, then the book appears to cover a breath of topics that would be of significant interest." (Brain Injury, Vol. 15, No. 3, 2001)

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
John Wiley & Sons Inc
Date d'édition
1999
Langue
anglais
ISBN 10 
0471183474
ISBN 13 
9780471183471
Reliure
Relié
Nombre de pages
456
Éditeur
Miller Leonard P.
Coordonnées du fabricant
non disponible
Personne responsable
non disponible