Gene Transfer in Neuroscience: Towards Gene Therapy of Neurological Disorders - Couverture souple

Couverture souple

ISBN 10 : 0471957666 ISBN 13 : 9780471957669

Editeur : John Wiley & Sons Ltd, 1996

Synopsis

This is a study of the latest techniques used by gene delivery laboratories. The methodology under discussion includes physical transfection techniques, various viral vectors, and retrovirally-transduced cell and bone marrow transplantation. Several variations of a single protocol are given, thus demonstrating how different labs have solved a common problem in different ways. The protocols are also indexed and cross-referenced so that an investigator can find all the details required for a particular problem.

A propos du livre

Présentation de l'éditeur

Protocols for Gene Transfer in Neuroscience Towards Gene Therapy of Neurological Disorders Edited by P. R. Lowenstein University of Manchester, UK and L. W. Enquist Princeton University, USA The brain and the cells that compose it have always presented unique barriers to any kind of outside interventions, including drug delivery, surgical procedures and the genetic manipulation of cells. However, these barriers are now being bypassed by the new technology of gene delivery. Protocols for Gene Transfer in Neuroscience is the first practical guide to gene delivery, providing over 150 easy to follow, step–by–step protocols, together with troubleshooting hints and the theoretical background needed for neuroscientists to understand, adapt and expand the technology as needed. Written by a team of international expert neuroscientists, geneticists, molecular biologists and biochemists, Protocols for Gene Transfer in Neuroscience describes the latest techniques from the top gene–delivery labs, ranging from physical transfection techniques, through the use of a wide range of viral vectors, to retrovirally transduced cell and bone marrow transplantation. Several variations of a single protocol are given, thus demonstrating how different labs have solved a common problem in different ways. The protocols are also indexed and cross–referenced so that an investigator can find all the details required for a particular problem.

Quatrième de couverture

The brain and the cells that compose it have always presented unique barriers to any kind of outside interventions, including drug delivery, surgical procedures and the genetic manipulation of cells. However, these barriers are now being bypassed by the new technology of gene delivery. Protocols for Gene Transfer in Neuroscience is the first practical guide to gene delivery, providing over 150 easy to follow, step–by–step protocols, together with troubleshooting hints and the theoretical background needed for neuroscientists to understand, adapt and expand the technology as needed. Written by a team of international expert neuroscientists, geneticists, molecular biologists and biochemists, Protocols for Gene Transfer in Neuroscience describes the latest techniques from the top gene–delivery labs, ranging from physical transfection techniques, through the use of a wide range of viral vectors, to retrovirally transduced cell and bone marrow transplantation. Several variations of a single protocol are given, thus demonstrating how different labs have solved a common problem in different ways. The protocols are also indexed and cross–referenced so that an investigator can find all the details required for a particular problem.

Détails de l'édition

• Éditeur: John Wiley & Sons Ltd
• Date d'édition: 1996
• Langue: anglais
• ISBN 10: 0471957666
• ISBN 13: 9780471957669
• Reliure: Broché
• Nombre de pages: 446
• Éditeur: Lowenstein Pedro, Enquist Lynn W.
• Coordonnées du fabricant: non disponible
• Personne responsable: non disponible