Neuronal Mechanism Memory Formation: Concepts of Long-term Potentiation and Beyond - Couverture souple

H¿lscher, Christian

 
9780521018036: Neuronal Mechanism Memory Formation: Concepts of Long-term Potentiation and Beyond

Synopsis

An international group of scientists discuss the latest work on long-term potentiation (LTP), a model for encoding memory.

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Présentation de l'éditeur

Long-term potentiation (LTP) is by far the most dominant model for neuronal changes that might encode memory. LTP is an elegant concept that meets many criteria set up by theoreticians long before the model's discovery, and it also fits anatomical data of learning-dependent synapse changes. Since the discovery of LTP, the question has remained about how closely LTP produced in vitro by artificial stimulation of neurons actually models putative learning-induced synaptic changes. A number of recent investigations have tried to correlate synaptic changes observed after learning with changes produced by artificial stimulation of neurons. These studies have failed to find a correlation between the two forms of synaptic plasticity. In this book, an international group of neurobiologists and psychologists discuss their latest ideas and data. The results of experiments using electrophysiological techniques in vitro are discussed and compared with the results of in vivo experiments. Learning experiments are also discussed. Theoretical models such as the Hebb theory of synaptic changes during learning are compared to different models that do not predict upregulation of synaptic transmission. A wide approach is taken, and research and models in different brain areas such as the neocortex and the basal brain are discussed.

Revue de presse

"...this volume can be recommended for those who wish to succinctly survey the current state of science... This book offers a timely collection of well-written articles..." Timothy J. Teyler, Quarterly Review of Biology

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Autres éditions populaires du même titre

9780521770675: Neuronal Mechanisms of Memory Formation: Concepts of Long-term Potentiation and Beyond

Edition présentée

ISBN 10 :  052177067X ISBN 13 :  9780521770675
Editeur : Cambridge University Press, 2000
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