Articles liés à Drug Resistance in Cancer: Mechanisms and Models

Drug Resistance in Cancer: Mechanisms and Models - Couverture rigide

Goldie, James H.; Coldman, Andrew J.

 
9780521482738: Drug Resistance in Cancer: Mechanisms and Models
Couverture rigide
ISBN 10 : 0521482739 ISBN 13 : 9780521482738
Editeur : Cambridge University Press, 1998

Synopsis

Drug resistance in cancer, whereby a proportion of cancer cells evades chemotherapy, poses a profound and continuing challenge for the effective treatment of cancer. The principles underlying the biological mechanisms behind this phenomenon are clearly understood and explained in this volume. However, a deeper understanding of drug resistance requires a quantitative appreciation of the dynamic forces that shape tumour growth, including spontaneous mutation and selection processes. The authors seek to explain and to simplify these complex mechanisms, and to place them in a clinical context. Clearly explained mathematical models are used to illustrate the biological principles and provide an insight into tumour development and the effectiveness and limitations of drug treatment. It is suitable for those with a non-mathematical background and aims to enhance the effectiveness of cancer therapy.

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Présentation de l'éditeur

Drug resistance in cancer, whereby a proportion of cancer cells evades chemotherapy, poses a profound and continuing challenge for the effective treatment of cancer. The principles underlying the biological mechanisms behind this phenomenon are clearly understood and explained in this volume. However, a deeper understanding of drug resistance requires a quantitative appreciation of the dynamic forces that shape tumour growth, including spontaneous mutation and selection processes. The authors seek to explain and to simplify these complex mechanisms, and to place them in a clinical context. Clearly explained mathematical models are used to illustrate the biological principles and provide an insight into tumour development and the effectiveness and limitations of drug treatment. It is suitable for those with a non-mathematical background and aims to enhance the effectiveness of cancer therapy.

Revue de presse

'However, this volume provides a very good overview of the drug resistance field with special emphasis on mathematical models and can be recommended to everyone interested in the field. Even those who see math as an alien subject will find this book useful, since the mathematical portions of the text have been kept as straightforward as possible. The book is a good source of references and suggestions for further reading and should interest a wide readership including clinicians, molecular biologists, and researchers interested in tumor growth, tumor killing and mutation models.' V. Spataro, Annals of Oncology

'... required reading for all trainees in oncology.' Paul P. Carbone, Oncology

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Éditeur
Cambridge University Press
Date d'édition
1998
Langue
anglais
ISBN 10 
0521482739
ISBN 13 
9780521482738
Reliure
Relié
Nombre de pages
256
Coordonnées du fabricant
non disponible
Personne responsable
Avery
https://www.avery.fr/

chemin des peupliers 27
Dardilly
France