Modulation MHC Antigen Expression - Couverture souple

Blair, G. Eric

Couverture souple

ISBN 10 : 0521499216 ISBN 13 : 9780521499217

Editeur : Cambridge University Press, 2008

Synopsis

Brings together basic aspects of the regulation of MHC antigens with important clinical applications.

A propos du livre

Présentation de l'éditeur

The major histocompatibility complex (MHC) genes are involved in the immune system's response to tumour and infected cells and in generating an immune response. This book brings together basic aspects of the regulation of MHC antigens with important clinical applications (in viral infection, viral oncology, cancer biology and autoimmunity). There is a strong emphasis on situations where MHC expression is modulated (either stimulated or repressed). The book's major themes are: the mechanisms of MHC expression explored at several levels including the transcription and translation of MHC genes and the insertion of MHC protein molecules into plasma membranes; the effect of cytokines on MHC expression both in the aetiology of certain diseases and in possible immunotherapeutic approaches to disease; and the use of gene therapy to modify MHC expression in cancer cells, and thereby cause tumour rejection.

Revue de presse

'This book is a superb summary of current understanding by some of the leading investigators.' David R. Johnson, BMJ

'... an excellent book which all immunologists should not only read but also buy, because of all the important information collected therein.' R. Wegmann, Cellular and Molecular Biology

'... for individuals interested in MHC biology in health and in disease, this book provides a timely and up-to-date review.' Alice Gottlieb, The Lancet

'... this book can be recommended as an excellent starting point for anyone who wishes to explore the field of MHC expression.' Stephen H. Powis, Immunology Today

' ... valuable.' SGM Quarterly

'... an indispensable reference for researchers and students in cell, developmental, and molecular biology and allied disciplines'. Anticancer Research

Détails de l'édition

• Éditeur: Cambridge University Press
• Date d'édition: 2008
• Langue: anglais
• ISBN 10: 0521499216
• ISBN 13: 9780521499217
• Reliure: Broché
• Nombre de pages: 460
• Coordonnées du fabricant: non disponible
• Personne responsable: Avery; https://www.avery.fr/; ; chemin des peupliers 27; Dardilly; France