How do we evaluate the safety and benefit of new drugs? What tasks do we hold the government responsible for and which ones do we leave to the medical profession? Harry Marks explores the origins of our contemporary system of drug regulation and the modern clinical trial. He shows that the story of modern drug regulation is synonymous with the history of therapeutic reform. Accompanying this history of public policy is a detailed account of changing experimental ideal and practices. Marks follows the history of therapeutic experimentation, from the 'collective investigations' of the last century to the controlled clinical trial which emerged after 1950 as the paradigm of scientific experimentation. The result is the first general history of clinical research in the United States, a book which examines therapeutic experiments in a wide range of diseases, from syphilis and pneumonia to heart disease and diabetes.
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'Harry Marks' book on science and therapeutic reform in the USA during the 20th century is the best available account of the progress of clinical experiment available, and nobody seriously interested in the topic can afford not to read it.' Endeavour
' ... the book has become essential reading for anyone thinking about the place of science within twentieth-century medicine.' Medical History
'The Progress of Experiment is a book rich in empirical detail, all meticulously documented in long footnotes. ... this book makes for interesting reading for anybody interested in arriving at a historically based judgement on the potential scope and limits of evidence-based medicine. With its detailed, well-researched case studies it will also provide good course reading. It is laudable that the paperback edition makes this book available to a wider group of potential readers.' The British Society for the History of Science
How do we evaluate the safety and benefit of new drugs? What tasks do we hold the government responsible for and which ones do we leave to the medical profession? Harry Marks explores the origins of our contemporary system of drug regulation and the modern clinical trial. He shows that the story of modern drug regulation is synonymous with the history of therapeutic reform. Accompanying this history of public policy is a detailed account of changing experimental ideal and practices. Marks follows the history of therapeutic experimentation, from the 'collective investigations' of the last century to the controlled clinical trial which emerged after 1950 as the paradigm of scientific experimentation. The result is the first general history of clinical research in the United States, a book which examines therapeutic experiments in a wide range of diseases, from syphilis and pneumonia to heart disease and diabetes.
Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.
Vendeur : BooksRun, Philadelphia, PA, Etats-Unis
Hardcover. Etat : Very Good. 1. It's a well-cared-for item that has seen limited use. The item may show minor signs of wear. All the text is legible, with all pages included. It may have slight markings and/or highlighting. N° de réf. du vendeur 0521581427-11-1
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Hardcover. Etat : Good. No Jacket. Missing dust jacket; Pages can have notes/highlighting. Spine may show signs of wear. ~ ThriftBooks: Read More, Spend Less. N° de réf. du vendeur G0521581427I3N01
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Vendeur : Solr Books, Lincolnwood, IL, Etats-Unis
Etat : good. This book is in Good condition. There may be some notes and highlighting but otherwise the book is in overall good condition. N° de réf. du vendeur BCV.0521581427.G
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Vendeur : Second Story Books, ABAA, Rockville, MD, Etats-Unis
Hardcover. Etat de la jaquette : dj. First Edition. Octavo, viii, xi, xii, 258 pages. In Very Good minus condition with a Very Good dust jacket. Dust jacket protected with a mylar covering. Spine orange with white lettering. Exterior has slight wear including faint sunning to the spine. Boards have extremely slight wear. Text block has very slight wear. Illustrated. First edition. NOTE: Shelved in Column N. 1415418. FP New Rockville Stock. N° de réf. du vendeur 1415418
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Vendeur : Washburn Books, Pateley Bridge, Royaume-Uni
Hardcover. Etat : Near Fine. y First Edition. Cambridge University Press, 1997. Book. Near Fine. Black Cloth Boards. First Edition. 8vo - over 7¾" - 9¾" tall. Examination of the beliefs and activities of 'therapeutic reformers', individuals who sought to use the science of controlled experiments to direct medical practice. 258pp with index. Gilt lettering to spine. Very slight bumping to spine, otherwise near fine unmarked copy. Book. N° de réf. du vendeur 012084
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Vendeur : Greener Books, London, Royaume-Uni
Hardcover. Etat : Used; Very Good. **SHIPPED FROM UK** We believe you will be completely satisfied with our quick and reliable service. All orders are dispatched as swiftly as possible! Buy with confidence! Greener Books. N° de réf. du vendeur 5086142
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Vendeur : History Bookshop, Ascott under Wychwood, OXON, Royaume-Uni
Hardcover. Etat : As New. Etat de la jaquette : As New. 1st Edition. N° de réf. du vendeur HB8502B027
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Vendeur : BennettBooksLtd, Los Angeles, CA, Etats-Unis
hardcover. Etat : New. In shrink wrap. Looks like an interesting title! N° de réf. du vendeur Q-0521581427
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Etat : New. N° de réf. du vendeur I-9780521581424
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Etat : New. N° de réf. du vendeur 844781-n
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