Gene Regulation: A Eukaryotic Perspective - Couverture souple

Latchman, David S.

 
9780748739776: Gene Regulation: A Eukaryotic Perspective

Synopsis

This is the third edition of a work which focuses on how cellular genes are regulated in eukaryotes. It incorporates advances which have occurred since the second edition was published in 1995, and also discusses several new topics in detail, to reflect their increasing importance. These include regulation of RNA transport, the SWI-SNF complex, the effect of specific transcription factors on histone acetylation, as well as the role of co-repressors/co-activators and the mediator complex by which the inhibitory or activating effects of transcription factors are often mediated. The most significant change in this edition, however, is the addition of a chapter describing the basic processes by which DNA is converted into RNA and then into protein.

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Présentation de l'éditeur

For this forth edition, the book has been updated thoroughly, with particular emphasis on modulation of chromatin structure by histone modifications/ remodelling complexes and the role of co-activators/ co-repressors. Methods used to analyse gene expression have also been given more attention, with a new section added on methods for examining DNA binding by transcription factors. Additionally, new sections have been added on coupling of transcription factors. Additionally, new sections have been added on coupling of transcription with post-transcriptional process and negatively acting sequence elements, which are of increasing prominence.

Présentation de l'éditeur

Gene regulation is an essential process in the development and maintenance of a healthy body, and as such, is a central focus in both basic science and medical research.  Gene Regulation, Fifth Edition provides the student and researcher with a clear, up-to-date description of gene regulation in eukaryotes, distilling the vast and complex primary literature into a concise overview.

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