The purpose of this book is to help chemists, biochemists and other scientists purify the chemical reagents which they use in their work. Despite the fact that commercially available chemicals are often of a very high quality, and quite satisfactory for some applications within science and technology, it is becoming almost as important to know what impurities are present and make allowance for them as to remove them completely. This book will show you how. The main chapters describe processes, taken from the literature, for purifying over 4000 organic and 750 inorganic and organometallic commercially available chemicals. Further chapters describe the methods and techniques currently used for purification in laboratories and prescribed in the text. Methods for purifying classes of chemicals where specific compounds are not treated individually in the text are dealt with in a separate chapter. This considerably expanded and revised fourth edition includes much new material dealing with modern reagents for natural products chemistry, protein biochemistry and molecular biology. It also includes many individual compounds not previously covered, and more information is given for most entries, including melting and boiling points, molecular weights, refractive indexes, densities and CAS registry numbers, as well as likely contaminants and storage conditions in appropriate cases.
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Wilfred L. F. Armarego graduated BSc (Hons) in 1953 and PhD from the University of London in 1956 and came to Australia in that year. After two years at the Central Research Laboratories (ICIANZ) in Melbourne, where he worked on plant growth substances, and one year on potentially carcinogenic polycyclic aromatic hydrocarbons at the University of Melbourne as Senior Demonstrator in Organic Chemistry, he joined the Department of Medical Chemistry as a Research Fellow in 1960. He became a Fellow in 1963 and was awarded a DSc degree (London) in 1968. He was promoted to Senior Fellow in 1967 and began research work on the biochemistry and molecular biology of pteridine-requiring enzymes related to the inherited metabolic disease phenylketonuria and its variants. He was head of the Protein Biochemistry Group and Pteridine Biochemistry Laboratory until his retirement in 1996. He is now a visiting fellow at the John Curtin School of Medical Research, and member of the editorial boards of ‘Medicinal Research Reviews’ and ‘Pteridines’ journals.
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