Articles liés à Drug Design for Neuroscience

Drug Design for Neuroscience - Couverture rigide

Kozikowski, Alan P.

 
9780781700610: Drug Design for Neuroscience

Synopsis

This volume brings together the work of leading medical chemists and represents efforts on the part of drug designers to produce small molecules aimed at preventing or treating brain-related diseases. Prominent among these are contributions on agents of value in Alzheimer's therapy; anxioselective anxiolytics; novel antipsychotics and the activation of dopamine autoreceptors; the role of the neurotransmitter dopamine in cocaine addiction; multiple populations of serotonin receptors; designing specific 5-HT3 receptor antagonists; glutamatergic receptor modulation; developing compounds capable of interacting with second messenger systems; and brain targeting of biologically active compounds. Also featured are examples of computer-assisted molecular modelling (CAMM) described throughout the text.

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