Description du livre Gebunden. Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. In the next couple of years the human genome will be fully sequenced. This will provide us with the sequence and overall function of all human genes as well as the complete genome for many micro-organisms. Subsequently it is hoped, by means of powerful . N� de r�f. du vendeur 5969571

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Virtual Screening: An Alternative or Complement to High Throughput Screening? : Proceedings of the Workshop �New Approaches in Drug Design and Discovery�, special topic �Virtual Screening�, Schlo� Rauischholzhausen, Germany, March 15�18, 1999

Gerhard Klebe

Edit� par Springer Netherlands (2000)

ISBN 10 : 0792366336 ISBN 13 : 9780792366331

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AHA-BUCH GmbH
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Description du livre Buch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - In the next couple of years the human genome will be fully sequenced. This will provide us with the sequence and overall function of all human genes as well as the complete genome for many micro-organisms. Subsequently it is hoped, by means of powerful bioinformatic tools, to determine the gene variants that contribute to various multifactorial diseases and genes that exist in certain infectious agents but not humans. As a consequence, this will allow us to define the most appropriate levels for drug intervention. It can be expected that the number of potential drug targets will increase, possibly by a factor of 10 or more. Nevertheless, sequencing the human genome or, for that matter, the genome of other species will only be the starting point for the understanding of their biological function. Structural genomics is a likely follow-up, combined with new techniques to validate the therapeutic relevance of such newly discovered targets. Accordingly, it can be expected that in the near future we will witness a substantial increase in novel putative targets for drugs. To address these new targets effectively, we require new approaches and innovative tools. At present, two alternative, yet complementary, techniques are employed: experimental high-throughput screening (HTS) of large compound libraries, increasingly provided by combinatorial chemistry, and computational methods for virtual screening and de novo design. As kind of status report on the maturity of virtual screening as a technique in drug design, the first workshop on new approaches in drug design and discovery was held in March 1999, at Schlo� Rauischholzhausen, near Marburg in Germany. More than 80 scientists gathered and discussed their experience with the different techniques. The speakers were invited to summarize their contributions together with their impressions on the present applicability of their approach. Several of the speakers followed this request which is summarized in this publication. N� de r�f. du vendeur 9780792366331

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Virtual Screening: An Alternative or Complement to High Throughput Screening: Proceedings of the Workshop, New Approaches in Drug Design and Discovery, Schlob rauischhol

Gerhard Klebe

Edit� par Kluwer Academic Pub (2000)

ISBN 10 : 0792366336 ISBN 13 : 9780792366331

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Description du livre Hardcover. Etat : Brand New. 295 pages. 9.75x6.75x0.75 inches. In Stock. N� de r�f. du vendeur x-0792366336

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Virtual Screening: An Alternative or Complement to High Throughput Screening?

Gerhard Klebe

Edit� par Springer Netherlands Nov 2000 (2000)

ISBN 10 : 0792366336 ISBN 13 : 9780792366331

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Description du livre Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In the next couple of years the human genome will be fully sequenced. This will provide us with the sequence and overall function of all human genes as well as the complete genome for many micro-organisms. Subsequently it is hoped, by means of powerful bioinformatic tools, to determine the gene variants that contribute to various multifactorial diseases and genes that exist in certain infectious agents but not humans. As a consequence, this will allow us to define the most appropriate levels for drug intervention. It can be expected that the number of potential drug targets will increase, possibly by a factor of 10 or more. Nevertheless, sequencing the human genome or, for that matter, the genome of other species will only be the starting point for the understanding of their biological function. Structural genomics is a likely follow-up, combined with new techniques to validate the therapeutic relevance of such newly discovered targets. Accordingly, it can be expected that in the near future we will witness a substantial increase in novel putative targets for drugs. To address these new targets effectively, we require new approaches and innovative tools. At present, two alternative, yet complementary, techniques are employed: experimental high-throughput screening (HTS) of large compound libraries, increasingly provided by combinatorial chemistry, and computational methods for virtual screening and de novo design. As kind of status report on the maturity of virtual screening as a technique in drug design, the first workshop on new approaches in drug design and discovery was held in March 1999, at Schlo� Rauischholzhausen, near Marburg in Germany. More than 80 scientists gathered and discussed their experience with the different techniques. The speakers were invited to summarize their contributions together with their impressions on the present applicability of their approach. Several of the speakers followed this request which is summarized in this publication. 312 pp. Englisch. N� de r�f. du vendeur 9780792366331

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Virtual Screening

. Ed(s): Klebe, Gerhard

Edit� par Kluwer Academic Publishers (2000)

ISBN 10 : 0792366336 ISBN 13 : 9780792366331

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Kennys Bookshop and Art Galleries Ltd.
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Description du livre Etat : New. The first workshop on new approaches in drug design and discovery was held in March 1999, at Schloss Rauischholzhausen, near Marburg in Germany. The speakers were invited to summarize their contributions together with their impressions on the applicability of their approach. This title summerizes this request. Editor(s): Klebe, Gerhard. Num Pages: 295 pages, 35 black & white illustrations, 18 colour illustrations, biography. BIC Classification: MJA; MMG; TDCW. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 235 x 155 x 19. Weight in Grams: 688. . 2000. Reprinted from perspectives in drug discovery and. Hardback. . . . . N� de r�f. du vendeur V9780792366331

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