Structure-Based Drug Design - Couverture rigide

Couverture rigide

ISBN 10 : 0824798694 ISBN 13 : 9780824798697

Editeur : Routledge, 1997

Synopsis

Introducing the most recent advances in crystallography, nuclear magnetic resonance, molecular modeling techniques, and computational combinatorial chemistry, this unique, interdisciplinary reference explains the application of three-dimensional structural information in the design of pharmaceutical drugs. Furnishing authoritative analyses by world-renowned experts, Structure-Based Drug Design discusses protein structure-based design in optimizing HIV protease inhibitors and details the biochemical, genetic, and clinical data on HIV-1 reverse transcriptase presents recent results on the high-resolution three-dimensional structure of the catalytic core domain of HIV-1 integrase as a foundation for divergent combination therapy focuses on structure-based design strategies for uncovering receptor antagonists to treat inflammatory diseases demonstrates a systematic approach to the design of inhibitory compounds in cancer treatment reviews current knowledge on the Interleukin-1 (IL-1) system and progress in the development of IL-1 modulators describes the influence of structure-based methods in designing capsid-binding inhibitors for relief of the common cold and much more!

A propos du livre

À propos de l'auteur

Pandi Veerapandian

Détails de l'édition

• Éditeur: Routledge
• Date d'édition: 1997
• Langue: anglais
• ISBN 10: 0824798694
• ISBN 13: 9780824798697
• Reliure: Relié
• Nombre de pages: 664
• Éditeur: Veerapandian Pandi
• Coordonnées du fabricant: non disponible
• Personne responsable: non disponible