Reviews recent developments and progress in the carbohydrate-related chemistry of novel nucleic acid mimics and their applications in antisense therapeutics. Discusses the use of new chemical classes to rationally design and synthesize oligonucleotides. Explores several carbohydrate modifications of the oligonucleotide to stabilize against nuclease degradation and to enhance the binding affinity for a given target. Suggests future directions of carbohydrate-related modifications for antisense molecules.
Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.
Vendeur : Plurabelle Books Ltd, Cambridge, Royaume-Uni
Hardcover. Etat : Good. Series: ACS Symposium Series 232p laminated hardback, white cover, excellent condition, library bookplate and shelfmark, never used Language: English. N° de réf. du vendeur 180981
Quantité disponible : 1 disponible(s)