Glycomimetics: Modern Synthetic Methodologies - Couverture rigide

 
9780841238800: Glycomimetics: Modern Synthetic Methodologies
Couverture rigide
ISBN 10 : 0841238804 ISBN 13 : 9780841238800
Editeur : Oxford University Press Inc, 2005

Synopsis

Modern Synthetic Methodologies Toward Glycomimetics contains 10 chapters describing the syntheses of natural and non-natural glycomimetics using modern transition metal catalyzed reactions. This book also contains several experimental details allowing the readers to get familiar with such intricate reactions using complex alkylidene carbenoids, samarium diodide, dicobalt octacarbonyl alkyne cyclotrimerization, and the like. The descripitions of biologically active carbohydrates are elegantly detailed. A new solution-phase glycopeptide synthesis using unprotected glycosyl amino acids as phase-tags is also described. Important strategies into the design of complex sialic acid C-saccharides, aryl C-glycosides, and conformationally restricted analogs of the important sialyl Lewis X are discussed. Tethering of carbohydrate residues through ester bonds and applications of the Tebbe's methylenation and either ring closing metathesis or intramolecular C-glycosidations are used to provide novel carbohydrate analogs.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Modern Synthetic Methodologies Toward Glycomimetics contains 10 chapters describing the syntheses of natural and non-natural glycomimetics using modern transition metal catalyzed reactions. This book also contains several experimental details allowing the readers to get familiar with such intricate reactions using complex alkylidene carbenoids, samarium diodide, dicobalt octacarbonyl alkyne cyclotrimerization, and the like. The descripitions of biologically active carbohydrates are elegantly detailed. A new solution-phase glycopeptide synthesis using unprotected glycosyl amino acids as phase-tags is also described. Important strategies into the design of complex sialic acid C-saccharides, aryl C-glycosides, and conformationally restricted analogs of the important sialyl Lewis X are discussed. Tethering of carbohydrate residues through ester bonds and applications of the Tebbe's methylenation and either ring closing metathesis or intramolecular C-glycosidations are used to provide novel carbohydrate analogs.

Revue de presse

The book provides outstanding chapters by a highly recognised group of researchers that will serve as a valuable tool for well-trained traditional glycochemists and particularly for newcomers in the field of glycomimetics. Current Engineering Practice, Volume 48 2005.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
Oxford University Press Inc
Date d'édition
2005
Langue
anglais
ISBN 10 
0841238804
ISBN 13 
9780841238800
Reliure
Relié
Nombre de pages
202
Éditeur
Roy René
Coordonnées du fabricant
non disponible
Personne responsable
Messaggerie Libri
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