Radiotracers In Drug Development - Couverture rigide

Lappin, Graham; Temple, Simon

Couverture rigide

ISBN 10 : 0849333474 ISBN 13 : 9780849333477

Editeur : CRC Press Inc, 2006

Synopsis

Although there are numerous books on drug metabolism, Radiotracers in Drug Development is unique in explaining how radiotracers are used to elucidate a drug’s absorption, distribution, metabolism, and excretion (ADME). Covering traditional and recent technologies and applications, the book takes a strong industrial approach, discussing the basics of scintillation counting and untangling the various data processing methods often specific to individual manufacturers.

The chapters include descriptions of the latest micro-plate counters and the growing applications of accelerator mass spectrometry, positron emission tomography, gamma-scintigraphy, and radioluminography. In addition to describing how the analytical technologies work, the contributors explain how the data are interpreted and used in the drug registration process.

A unique reference and training aid essential for every drug metabolism department or drug metabolism research team, the book provides insight into the use and practice of ADME in a way that is both instructive and practical. Moving easily across the boundaries of biology, chemistry, and physics, this is the only comprehensive, interdisciplinary resource covering the how-tos of employing radiotracers in drug development. It provides detailed information on how the science is relevant to the registration process.

A propos du livre

À propos de l'auteur

Graham Lappin, Simon Temple

Détails de l'édition

• Éditeur: CRC Press Inc
• Date d'édition: 2006
• Langue: anglais
• ISBN 10: 0849333474
• ISBN 13: 9780849333477
• Reliure: Relié
• Nombre de pages: 300
• Coordonnées du fabricant: non disponible
• Personne responsable: non disponible