Computer Techniques in Preclinical and Clinical Drug Development - Couverture rigide

Jackson, Robert C.

Couverture rigide

ISBN 10 : 0849376823 ISBN 13 : 9780849376825

Editeur : CRC Press, 2019

Synopsis

It is estimated that 80 to 90% of drugs under development never make it to the marketplace due to insufficient clinical activity, unacceptable toxicity, rapid appearance of drug resistance, or other factors that should be, at least partially, predictable from preclinical testing. This new text asks the question, "How can we use computational methods to improve the success rate in drug development?" Computer Techniques in Preclinical and Clinical Drug Development shows how modeling makes it possible to extract the maximum amount of information and predictive value from preclinical data. Computer modeling methods from the areas of pharmacokinetics, pharmacodynamics, cytokinetics, and inhibition kinetics of multi-enzyme pathways are all discussed in this unique reference source.

A propos du livre

À propos de l'auteur

Jackson, Robert C.

Détails de l'édition

• Éditeur: CRC Press
• Date d'édition: 2019
• Langue: anglais
• ISBN 10: 0849376823
• ISBN 13: 9780849376825
• Reliure: Relié
• Nombre de pages: 238
• Coordonnées du fabricant: CRC Press; https://www.routledge-ny.com; ; 6000 BROKEN SOUND PARKWAY, NW SUITE 300; BOCA RATON; FL; 33487; Etats-Unis
• Personne responsable: gpsr@libri.de; gpsr@libri.de; ; Friedensallee 273; Hamburg; 22763; Allemagne