Anti-Infectives: Recent Advances in Chemistry & Structure Activity Relationships - Couverture rigide

Couverture rigide

ISBN 10 : 0854047077 ISBN 13 : 9780854047079

Editeur : Royal Society of Chemistry, 1997

Synopsis

This book contains recent advances in the chemistry of antibacterials/antibiotics, antifungals and antivirals, together with associated biological data and structure-activity relationships. The work described is of great breadth, embracing biosynthesis, total synthesis and partial (semi) synthesis of a wide variety of agents, including --lactams, oxazolidinones, streptogramins, azoles nucleosides and their analogues, strobilurin analogues, peptides and macrolides. It addresses a variety of microbial targets, such as reverse transcriptase, sialidase, cysteine proteases, chitin synthase, --lactamase, cell wall biosynthesis, signal peptidase, 14a-demethylase, HIV protese, as well as iron transport mechanisms, tubulins and mitochondrial respiration. Anti-Infectives highlights the seriousness of microbial resistance developing to mainline antimicrobials, and the work contained in it is bound to contribute to combatting this resistance in the future. As well as review material, it includes much research that has never previously been published, making it essential reading for both graduates and researchers in medicinal and pharmaceutical chemistry and related subjects.

Détails de l'édition

• Éditeur: Royal Society of Chemistry
• Date d'édition: 1997
• Langue: anglais
• ISBN 10: 0854047077
• ISBN 13: 9780854047079
• Reliure: Relié
• Nombre de pages: 350
• Éditeur: Bentley P H, O'Hanlon Peter J
• Coordonnées du fabricant: non disponible
• Personne responsable: non disponible