Cracking the Code - Couverture souple

Damiani, Stephen; Damiani, Sally; Kaminsky, Leah

Couverture souple

ISBN 10 : 0857984667 ISBN 13 : 9780857984661

Editeur : Vintage Australia, 2015

Synopsis

A family doctor shares a mother and father's determination to save their son. This story of a father's search to find a diagnosis, and ultimately a cure, for his son's mystery disease is an inspiration that has set the world of genetic medicine and research abuzz with the possibilities for the future. After Cracking the Code screened on "Australian Story," Stephen Damiani and his extraordinary ordinary family have been inundated with messages of support for Mission Massimo. Stephen has a background in construction economics and risk management. He teamed with geneticist Ryan Taft to map his family's genome in an attempt to discover the cause of his son's illness, and in the process developed a diagnostic tool that will revolutionize diagnoses and treatments of diseases as complex and rare as Massimo's leukodystrophy to widespread diseases such as diabetes and cardiovascular disease. Previously, trying to find a specific gene mutation that might be responsible for a disease was a million times harder than finding a needle in a haystack. Stephen's suggestion that Ryan align the genomes, or DNA blueprints, of himself, his wife Sally as well as Massimo, to find any unique variations and thereby create a smaller haystack was previously untried. Stephen convinced Massimo's neurologist, Dr. Rick Leventer at Melbourne's RCH, that it was just a case of technology, statistics, data, and money, but that it could be done. Once Taft was able to locate and isolate the specific genetic mutation of Massimo's DARS gene, the hunt was on to find other children with the same genetic mutation so that the diagnoses could be confirmed. With the help of Adeline Vanderver at the Washington DC-based Centre for Genetic Medicine and her Myelin Disorders Program, they were able to locate several other children with the DARS mutation and have now moved on to the next phase of Mission Massimo, finding a cure. Cracking the Code is simultaneously a wonderful family memoir and the story of some mind-blowing discoveries in medicine.

A propos du livre

À propos de l?auteur

Leah Kaminsky is an award-winning physician and writer, the poetry and fiction editor at the Medical Journal of Australia, and online editor at Hunger Mountain. The author of several books, she conceived and edited Writer, M.D., an anthology of contemporary doctor-writers. She was recently shortlisted in the Faulkner-Wisdom Novel Writing Competition. She holds an MFA in creative writing from Vermont College of Fine Arts. Stephen Diamanti is the father of three young boys. He has a broad commercial background in the corporate sector and, more recently, in his own start-up businesses. He recently established the Mission Massimo Foundation which aims to accelerate the discovery of novel genetic variations responsible for pediatric white matter disorders and to translate these findings into clinical trials and treatments.

Détails de l'édition

• Éditeur: Vintage Australia
• Date d'édition: 2015
• Langue: anglais
• ISBN 10: 0857984667
• ISBN 13: 9780857984661
• Reliure: Broché
• Numéro d'édition: 1
• Nombre de pages: 320
• Coordonnées du fabricant: non disponible
• Personne responsable: non disponible