Leading basic and clinical investigators from around the world summarize the most recent research on the molecular and cellular origins of lupus. Their cutting-edge articles review the mechanisms underlying abnormal immunity and introduce the powerful new concept that a disorder of multiple genes underlies the abnormal immune response, leading directly to the development of lupus. This pathophysiology is shown to involve a wide variety of cell types, including T cells, B cells, natural killer cells, macrophages/monocytes, and endothelial cells. Over time, the resulting long-term inflammation causes irreversible cell destruction and, ultimately, organ failure. Lupus: Molecular and Cellular Pathogenesis is a masterful new synthesis of all the new knowledge emerging today about lupus. Its new perspectives will sharpen the focus of research and ultimately lead to better and more effective treatment.
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Gebunden. Etat : New. Leading basic and clinical investigators from around the world summarize the most recent research on the molecular and cellular origins of lupus. Their cutting-edge articles review the mechanisms underlying abnormal immunity and introduce the powerful new c. N° de réf. du vendeur 458446258
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Etat : New. Summarizes the research on the molecular and cellular origins of lupus. This title includes articles that review the mechanisms underlying abnormal immunity and introduce the concept that a disorder of multiple genes underlies the abnormal immune response, leading directly to the development of lupus. Editor(s): Tsokos, George C.; Kammer, Gary M. Series: Contemporary Immunology. Num Pages: 729 pages, 38 black & white illustrations, biography. BIC Classification: MJK; MNS. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 254 x 178 x 39. Weight in Grams: 1515. . 1999. Hardback. . . . . N° de réf. du vendeur V9780896035560
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