Kidney in Essential Hypertension: Proceedings of the Course on the Kidney in Essential Hypertension, Held New Orleans, La, March 18-19, 1983 - Couverture rigide

Couverture rigide

ISBN 10 : 0898386160 ISBN 13 : 9780898386165

Editeur : Kluwer Academic Publishers, 1983

Synopsis

The kidney, similar to the heart, plays a three-fold role in essential hypertension. First, it participates in the patho- genesis of arterial hypertension. Second, it suffers as a target organ of long-standing hypertension, and third, it experiences the effects of antihypertensive therapy. Perhaps most contested at the present time is the involvement of the kidney in the patho- genesis of essential hypertension. More than a century ago, William Osler put forward three basic hypotheses about the "genuine contracted kidney. "l 1. "The hypertrophy can be regarded as an effect to overcome a sort of stop-cock action of the vessels when under the influence of an irritating ingredient in the blood greatly contracted and increased the peripheral resistance. " Clearly this hypothesis of an "irritating ingredient" is perhaps the most convincing nowadays, and numerous attempts have been made to identify a specific vasoconstrictive agent in the blood in essential hypertension. 2. "The obliteration of a large number of capillary territories in the kidney materially raised the arterial pressure. An additional factor of dimin- ished excretion of water also heightened the pressure within the blood vessel. " Today we know that fluid volume overload in the presence of reduced renal mass seems to be the most likely mechanism accoun- ting for renal parenchymal hypertension and, as shown by Guyton's group, for certain forms of experimental hypertension. 3.

Détails de l'édition

• Éditeur: Kluwer Academic Publishers
• Date d'édition: 1983
• Langue: anglais
• ISBN 10: 0898386160
• ISBN 13: 9780898386165
• Reliure: Relié
• Nombre de pages: 272
• Éditeur: Messerli Franz H.
• Coordonnées du fabricant: non disponible
• Personne responsable: CMN Printpool Inh. Mathis Neumann; https://www.also.com/ec/cms5/en_6000/6000/index.jsp; ; Friedrich-Karl-Str. 9; Hamburg; Allemagne