Personalized drug screening for functional tumor profiling - Couverture souple

El-Khoury, Victoria

Couverture souple

ISBN 10 : 1009016938 ISBN 13 : 9781009016933

Editeur : Cambridge University Press, 2022

Synopsis

Despite considerable advances in our understanding of the biology that underlies tumor development and progression of cancer and the rapidly evolving field of personalized medicine, cancer is still one of the deadliest diseases. Many cancer patients have benefited from the survival improvements observed with targeted therapies but only a small subset of patients receiving targeted drugs experience an objective response. Because cancer is a complex and heterogeneous disease, the search for effective cancer treatments will need to address not only patient-specific molecular defects but also aspects of the tumor microenvironment. The functional tumor profiling directly measures the cellular phenotype, in particular tumor growth, in response to drugs using patient-derived tumor models and might be the next step toward precision oncology. In this Element, the authors discuss the personalized drug screening as a novel patient stratification strategy for the determination of individualized treatment choices in oncology.

Détails de l'édition

• Éditeur: Cambridge University Press
• Date d'édition: 2022
• Langue: anglais
• ISBN 10: 1009016938
• ISBN 13: 9781009016933
• Reliure: Broché
• Nombre de pages: 30
• Coordonnées du fabricant: non disponible
• Personne responsable: Avery; https://www.avery.fr/; ; chemin des peupliers 27; Dardilly; France