Optimal Fractionation in Radiotherapy - Couverture rigide

Ghate, Archis

Couverture rigide

ISBN 10 : 1009341138 ISBN 13 : 9781009341134

Editeur : Cambridge University Press, 2023

Synopsis

This monograph provides a mathematically rigorous overview of optimal fractionation in cancer radiotherapy, which seeks to address the fundamental tradeoff of maximizing tumor-kill while protecting nearby healthy tissue from toxic effects. Most mathematical research on exact solutions to this problem is scattered across journals in applied mathematics, operations research, radiobiology, medicine, and medical physics. These works rarely include rigorous proofs or detailed derivations of their methodologies. Moreover, computer programs utilized for conducting numerical experiments seldom accompany these publications, thereby jeopardizing reproducibility. This monograph aims to provide a comprehensive pedagogical reference that brings researchers up to speed on optimal fractionation, utilizing and illustrating analytical techniques from linear algebra, calculus, linear programming, quadratic and nonlinear programming, robust optimization, and inverse optimization. Its purpose is to help readers understand the mathematics behind the optimal fractionation problem, empowering them to contribute original work to this field.

A propos du livre

À propos de l?auteur

Archis Ghate is a Professor of Industrial & Systems Engineering at the University of Washington, where he previously served for five years as the College of Engineering Endowed Professor of Healthcare Operations Research. His research focuses on optimization. He received a PhD in Industrial and Operations Engineering from the University of Michigan in 2006 and an M.S. in Management Science and Engineering from Stanford University in 2003.

Détails de l'édition

• Éditeur: Cambridge University Press
• Date d'édition: 2023
• Langue: anglais
• ISBN 10: 1009341138
• ISBN 13: 9781009341134
• Reliure: Relié
• Nombre de pages: 168
• Coordonnées du fabricant: non disponible
• Personne responsable: Avery; https://www.avery.fr/; ; chemin des peupliers 27; Dardilly; France