Genome-Scale Algorithm Design: Bioinformatics in the Era of High-Throughput Sequencing - Couverture rigide

Mäkinen, Veli; Belazzougui, Djamal; Cunial, Fabio; Tomescu, Alexandru I.

Couverture rigide

ISBN 10 : 1009341235 ISBN 13 : 9781009341233

Editeur : Cambridge University Press, 2023

Synopsis

Presenting the fundamental algorithms and data structures that power bioinformatics workflows, this book covers a range of topics from the foundations of sequence analysis (alignments and hidden Markov models) to classical index structures (k-mer indexes, suffix arrays, and suffix trees), Burrows-Wheeler indexes, graph algorithms, network flows, and a number of advanced omics applications. The chapters feature numerous examples, algorithm visualizations, and exercises, providing graduate students, researchers, and practitioners with a powerful algorithmic toolkit for the applications of high-throughput sequencing. An accompanying website (www.genome-scale.info) offers supporting teaching material. The second edition strengthens the toolkit by covering minimizers and other advanced data structures and their use in emerging pangenomics approaches.

A propos du livre

À propos des auteurs

Veli Mäkinen is Professor of Computer Science at the University of Helsinki, where he leads a research team on genome-scale algorithmics. He has taught advanced courses on algorithm design and analysis, string processing, data compression, and algorithmic genome analysis, as well as introductory courses on bioinformatics.

Djamal Belazzougui is a permanent researcher at the Research Centre for Scientific and Technical Information in Algiers, Algeria. He worked in the Genome-Scale Algorithmics group at the University of Helsinki as a postdoctoral researcher from 2012 to 2015. His research topics include hashing, succinct and compressed data structures, string algorithms, and bioinformatics.

Fabio Cunial is a computational scientist at the Broad Institute of MIT and Harvard. He has served as a postdoctoral researcher at the Genome-Scale Algorithmics group at the University of Helsinki as well as at the Myers lab in Dresden.

Détails de l'édition

• Éditeur: Cambridge University Press
• Date d'édition: 2023
• Langue: anglais
• ISBN 10: 1009341235
• ISBN 13: 9781009341233
• Reliure: Relié
• Numéro d'édition: 2
• Nombre de pages: 487
• Coordonnées du fabricant: non disponible