Redox Regulation of Differentiation and De-differentiation - Couverture souple

Couverture souple

ISBN 10 : 1032068426 ISBN 13 : 9781032068428

Editeur : CRC Press, 2024

Synopsis

Cell differentiation and the development of multicellular organisms are processes of self-assembly, controlled and driven by signaling molecules and cascades including redox regulation. These reactions may have provided the energy for the first metabolic steps in the evolution of life. Today, redox modifications are established as important regulatory events in cellular functions including differentiation and development. Redox modifications of single cysteines regulate differentiation of stem cells, formation of functioning organs, and de-differentiation such as formation of cancer cells. Current cancer therapy is based on redox events as well and regeneration often reactivates developmental pathways. Understanding differentiation and de-differentiation on a molecular level is therefore a prerequisite for the continuing development of new medical therapies. This book summarizes the roles of redox regulation in development by bringing together different concepts and comparing similarities and differences between various cell types and species. An international team of contributors presents several new aspects of redox-regulated differentiation and de-differentiation, including aspects of redox medicine.

Key Features

Provides the first summary on this important topic

Reviews redox-dependent development of model organisms and single organs

Highlights the redox-regulated pathways important for differentiation processes

Illustrates the potential of redox medicine

Combines state-of-the-art knowledge in differentiation/development, aging/longevity, and repair/regeneration

Written by leading experts in the field

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A propos du livre

À propos de l'auteur

Carsten Berndt is in the Department of Neurology, Heinrich-Heine-Universität Düsseldorf. He is the author or co-author of over 50 peer revidewed scholarly publications. His research has focuesd on the essential role of redox regulation in health and disease. Christopher Horst Lillig is at the Institute for Medical Biochemistry and Molecular Biology at the University of Greifswald.

Détails de l'édition

• Éditeur: CRC Press
• Date d'édition: 2024
• Langue: anglais
• ISBN 10: 1032068426
• ISBN 13: 9781032068428
• Reliure: Broché
• Nombre de pages: 392
• Éditeur: Berndt Carsten, Lillig Christopher
• Coordonnées du fabricant: non disponible
• Personne responsable: gpsr@libri.de; gpsr@libri.de; ; Friedensallee 273; Hamburg; 22763; Allemagne