Computer-Aided Design of Antimicrobial Lipopeptides as Prospective Drug Candidates - Couverture souple

Eswari, Jujjvarapu Satya; Dhagat, Swasti; Yadav, Manisha

Couverture souple

ISBN 10 : 1032238771 ISBN 13 : 9781032238777

Editeur : CRC Press, 2021

Synopsis

Increase in antibiotic resistance has forced researchers to develop new drugs against microorganisms. Lipopeptides are produced as secondary metabolites by some microorganisms. Computer-aided Design of Antimicrobial Lipopeptides as Prospective Drug Candidates provides the identification of novel ligands for different antimicrobial lipopeptides. Along with identification, it also provides some of the in silico drug design processes, namely homology modelling, molecular docking, QSAR studies, drug ADMET studies and pharmacophore studies to check the ligand-lipopeptide interaction. Some lipopeptides have shown anti-cancerous properties too, and this book discusses the required templates to design new drugs using computational techniques.

Key Features:

• Focuses on the use lipopeptides as new antimicrobial compounds
• Presents the basics of in silico modelling for design and development of new drug molecules, and is therefore of interest to beginners in the field
• Provides a step-by-step process for identification of drug molecules and testing its efficacy in silico
• Couples with courses on patents and intellectual property rights

A propos du livre

À propos de l'auteur

Jujjavarapu Satya Eswari is as an Assistant Professor in Department of Biotechnology at National Institute of Technology (NIT), Raipur, India. She specialises in biotechnology, process modelling, evolutionary optimization, and artificial intelligence.

Swasti Dhagat is a Research Scholar in Department of Biotechnology at National Institute of Technology Raipur, India. She has five research publications in peer-reviewed journals and an international conference proceeding in the field of in silico drug design of lipopeptides.

Manisha Yadav is a Research Scholar in Department of Biotechnology at National Institute of Technology Raipur, India. Her area of specialization is in the field of Bioinformatics with the expertise in various computational tools and software of genomics, proteomics, and drug design and discovery.

À propos de la quatrième de couverture

The authors focus on the properties of various lipopeptides which are produced as metabolites by bacteria and have shown to have antimicrobial properties. They provide a step-by-step method in identifying drug molecules for target compounds and testing various properties for drug efficacy. Both experienced researchers and beginners will benefit.

Détails de l'édition

• Éditeur: CRC Press
• Date d'édition: 2021
• Langue: anglais
• ISBN 10: 1032238771
• ISBN 13: 9781032238777
• Reliure: Broché
• Nombre de pages: 146
• Coordonnées du fabricant: non disponible
• Personne responsable: gpsr@libri.de; gpsr@libri.de; ; Europaallee 1; Bad Hersfeld; 36244; Allemagne