Bioinformatics of Autoimmune Diseases - Couverture souple

Ismail, Hamid D.

Couverture souple

ISBN 10 : 1041166117 ISBN 13 : 9781041166115

Editeur : CRC Press, 2026

Synopsis

Autoimmune diseases arise when the immune system misidentifies the body’s own tissues as threats, a catastrophic failure of self-recognition that leads to chronic inflammation, tissue damage, and long-term disability. Bioinformatics of Autoimmune Diseases is a timely and comprehensive guide that explores not only the immunological basis of these disorders but also the cutting-edge bioinformatics approaches used to analyze the genomic, transcriptomic, and epigenomic data driving modern discovery.

Structured to bridge foundational immunology with advanced computational analysis, this book offers readers a progression from the molecular mechanisms of immune function and dysfunction to the bioinformatics pipelines used to investigate them. Early chapters provide a thorough grounding in immune cell biology, immune checkpoints, and disease pathogenesis. Subsequent chapters guide readers through practical analyses of autoimmune disease data, covering RNA-Seq, variant analysis, microbiome profiling, ATAC-Seq, ChIP-Seq, single-cell sequencing, and gene therapy and autoimmune diseases. Bioinformatics tools are introduced using Python with step-by-step workflows, enabling hands-on engagement with real datasets.

Written by a professor of bioinformatics and developer of bioinformatics tools, the book draws from over a decade of broad experience in computational biology. With detailed illustrations, curated datasets, and a clear emphasis on reproducibility, it serves as a foundational resource for graduate students, clinicians, biomedical researchers, and anyone seeking to decode the bioinformatics foundations and mechanisms driving autoimmune disease.

A propos du livre

À propos de l'auteur

Hamid D. Ismail is a bioinformatics scholar and research high-performance computing center administrator. His research bridges biology and computation, focusing on bioinformatics tools, disease genomics, and machine learning. He is the author of several acclaimed textbooks that advance education and research in computational biology and genomics.

Détails de l'édition

• Éditeur: CRC Press
• Date d'édition: 2026
• Langue: anglais
• ISBN 10: 1041166117
• ISBN 13: 9781041166115
• Reliure: Broché
• Nombre de pages: 384
• Coordonnées du fabricant: CRC Press; https://www.routledge-ny.com; ; 6000 BROKEN SOUND PARKWAY, NW SUITE 300; BOCA RATON; FL; 33487; Etats-Unis
• Personne responsable: non disponible