NF-κB Transcription Factors: Methods and Protocols - Couverture souple

Couverture souple

ISBN 10 : 1071616714 ISBN 13 : 9781071616710

Editeur : Humana, 2022

Synopsis

This detailed book serves as a systematic examination of the analytical methods to study the transcription factor NF-κB in physiology and disease. It provides an up-to-date guidebook to navigate both conventional and highly specialized methods to detect and analyze the different signaling pathways of NF-κB activation and contextualize them within organismal physiology and disease pathogenesis, using genetic and biochemical techniques and some of the most advanced computational and systems biology methods. Additionally, the volume includes several examples of approaches utilized by leading experts in the NF-κB field to analyze and modulate NF-κB signaling in specific physiological and disease contexts, along with some of the most promising approaches to pharmacologically target the NF-κB pathway in human disease. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, NF-κB Transcription Factors: Methods and Protocols is an up-to-date guide intended for both basic and translational scientists who are working in the dynamic NF-κB field.

Détails de l'édition

• Éditeur: Humana
• Date d'édition: 2022
• Langue: anglais
• ISBN 10: 1071616714
• ISBN 13: 9781071616710
• Reliure: Broché
• Nombre de pages: 376
• Éditeur: Franzoso Guido, Zazzeroni Francesca
• Coordonnées du fabricant: Springer Nature Customer Service Center GmbH; ProductSafety@springernature.com; ; Europaplatz 3; Heidelberg; 69115; Allemagne