Cell-Wide Identification of Metabolite protein Interactions - Couverture rigide

Couverture rigide

ISBN 10 : 107162623X ISBN 13 : 9781071626238

Editeur : Humana, 2022

Synopsis

1. Protein-Metabolite Interactions Shape Cellular Metabolism and Physiology

Prathibha Muralidhara and Jennifer C. Ewald

2. Affinity Purification Protocol Starting with a Small Molecule as Bait

Nicolas E. Figueroa, Itzell E. Hernandez-Sanchez, Israel Maruri-Lopez, and Monika Chodasiewicz

3. Cellular Thermal Shift Assay for the Detection of Small Molecule-Target Interactions in Arabidopsis Cells

Qing Lu and Eugenia Russinova

4. Solvent-Induced Protein Precipitation for Drug Target Discovery

Xiaolei Zhang, Lianghai Hu, and Mingliang Ye

5. Identification of Plant Protein-Metabolite Interactions by Limited Proteolysis-Coupled Mass Spectrometry (LiP-MS)

Jhon Venegas-Molina, Petra Van Damme, and Alain Goossens

6. Limited Proteolysis-Mass Spectrometry to Identify Metabolite-Protein Interactions

Ales Holfeld, Jan-Philipp Quast, Roland Bruderer, Lukas Reiter, Natalie de Souza, and Paola Picotti

7. Proteome Integral Solubility Alteration (PISA) for High-Throughput Ligand Target Deconvolution with Increased Statistical Significance and Reduced Sample Amount

Massimiliano Gaetani and Roman A. Zubarev

8. Parallel Analysis of Protein-Protein and Protein-Metabolite Complexes Using a Single-Step Affinity Purification

Marcin Luzarowski and Aleksandra Skirycz

9. Detecting and Characterizing Interactions of Metabolites with Proteins by Saturation Transfer Difference Nuclear Magnetic Resonance (STD-NMR) Spectroscopy

Ruslan Nedielkov and Heiko M. Möller

10. PROMIS: Co-Fractionation Mass Spectrometry for Analysis of Protein-Metabolite Interactions

Marcin Luzarowski, Ewelina M. Sokolowska, Dennis Schlossarek, and Aleksandra Skirycz

11. Metabolomics: Going Deeper, Going Broader, Going Further

Sofia Moco and Joerg M. Buescher

12. Specifics of Metabolite-Protein Interactions and Their Computational Analysis and Prediction

Dirk Walther

13. Biophysical Approaches for the Characterization of Protein-Metabolite Interactions

Anja Thalhammer and Nina K. Bröker

14. Databases and Tools to Investigate Protein-Metabolite Interactions

Leonardo Perez de Souza and Alisdair R. Fernie

Détails de l'édition

• Éditeur: Humana
• Date d'édition: 2022
• Langue: anglais
• ISBN 10: 107162623X
• ISBN 13: 9781071626238
• Reliure: Relié
• Nombre de pages: 270
• Éditeur: Skirycz Aleksandra, Luzarowski Marcin, Ewald Jennifer C.
• Coordonnées du fabricant: Springer Nature Customer Service Center GmbH; ProductSafety@springernature.com; ; Europaplatz 3; Heidelberg; 69115; Allemagne