Poly(ADP-Ribose) Polymerase: Methods and Protocols - Couverture souple

 
9781071628935: Poly(ADP-Ribose) Polymerase: Methods and Protocols

Synopsis

This detailed volume explores poly(ADP-ribose) polymerases (PARPs) in the biology of eukaryotes and their relevance to human health. Beginning with a section on the detection and quantification of poly(ADP-ribose) polymer (pADPr), the book continues by delving into the identification of protein targets, functional analysis, the poly(ADP-ribosyl)ating pathway in chromatin and genes expression, as well as the use of animal models and PARP1 inhibitor design and testing, and more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 
Authoritative and up-to-date, Poly(ADP-Ribose) Polymerase: Methods and Protocols, Third Edition presents essential new and classical methods for studying the pADPr-pathway.

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Autres éditions populaires du même titre

9781071628904: Poly(adp-ribose Polymerase: Methods and Protocols

Edition présentée

ISBN 10 :  1071628909 ISBN 13 :  9781071628904
Editeur : Springer-Verlag New York Inc., 2022
Couverture rigide