Gapmers: Methods and Protocols (Methods in Molecular Biology, 3065) - Couverture rigide

Couverture rigide

ISBN 10 : 1071654756 ISBN 13 : 9781071654750

Editeur : Humana, 2026

Synopsis

This new edition reflects the progression of gapmer research from conceptual foundations to experimental implementation and analytical detection. Beginning with a section covering historical perspectives and the clinical context of antisense gapmers, the book continues with molecular design principles, experimental strategies for developing effective antisense oligonucleotides, methods to evaluate their efficacy and selectivity in cellular and animal models, and analytical approaches for detecting and quantifying antisense oligonucleotides in biological samples. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detailed implementation advice needed to ensure success in the lab.

Authoritative and up-to-date, Gapmers: Methods and Protocols, Second Edition serves as a valuable resource for researchers and clinicians aiming to accelerate the development of next-generation antisense therapeutics.

A propos du livre

À propos de la quatrième de couverture

This new edition reflects the progression of gapmer research from conceptual foundations to experimental implementation and analytical detection. Beginning with a section covering historical perspectives and the clinical context of antisense gapmers, the book continues with molecular design principles, experimental strategies for developing effective antisense oligonucleotides, methods to evaluate their efficacy and selectivity in cellular and animal models, and analytical approaches for detecting and quantifying antisense oligonucleotides in biological samples. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detailed implementation advice needed to ensure success in the lab.

Authoritative and up-to-date, Gapmers: Methods and Protocols, Second Edition serves as a valuable resource for researchers and clinicians aiming to accelerate the development of next-generation antisense therapeutics.

Détails de l'édition

• Éditeur: Humana
• Date d'édition: 2026
• Langue: anglais
• ISBN 10: 1071654756
• ISBN 13: 9781071654750
• Reliure: Gebundene Ausgabe
• Numéro d'édition: 2
• Nombre de pages: 328
• Éditeur: Yokota Toshifumi, Maruyama Rika, Moriyama Hidenori
• Coordonnées du fabricant: Springer Nature Customer Service Center GmbH; ProductSafety@springernature.com; ; Europaplatz 3; Heidelberg; 69115; Allemagne