Understanding mechanisms of gene regulation that are independent of the DNA sequence itself - epigenetics - has the potential to overthrow long-held views on central topics in biology, such as the biology of disease or the evolution of species. High throughput technologies reveal epigenetic mechanisms at a genome-wide level, giving rise to epigenomics as a new discipline with a distinct set of research questions and methods. Leading experts from academia, the biotechnology and pharmaceutical industries explain the role of epigenomics in a wide range of contexts, covering basic chromatin biology, imprinting at a genome-wide level, and epigenomics in disease biology and epidemiology. Details on assays and sequencing technology serve as an up-to-date overview of the available technological tool kit. A reliable guide for newcomers to the field as well as experienced scientists, this is a unique resource for anyone interested in applying the power of twenty-first-century genomics to epigenetic studies.
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Krishnarao Appasani is the Founder and Chief Executive Officer of GeneExpression Systems, a conference producing organization focusing on Biomedical and Physical Sciences. He is editor of MicroRNAs: From Basic Science to Disease Biology (2007) and RNA Interference: From Basic Science to Drug Development (2005), also published by Cambridge University Press.
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Paperback. Etat : new. Paperback. Understanding mechanisms of gene regulation that are independent of the DNA sequence itself - epigenetics - has the potential to overthrow long-held views on central topics in biology, such as the biology of disease or the evolution of species. High throughput technologies reveal epigenetic mechanisms at a genome-wide level, giving rise to epigenomics as a new discipline with a distinct set of research questions and methods. Leading experts from academia, the biotechnology and pharmaceutical industries explain the role of epigenomics in a wide range of contexts, covering basic chromatin biology, imprinting at a genome-wide level, and epigenomics in disease biology and epidemiology. Details on assays and sequencing technology serve as an up-to-date overview of the available technological tool kit. A reliable guide for newcomers to the field as well as experienced scientists, this is a unique resource for anyone interested in applying the power of twenty-first-century genomics to epigenetic studies. Leading experts from academia and both the biotechnology and pharmaceutical industries introduce the emerging field of epigenomics, covering a wide range of topics and methods such as basic chromatin biology, imprinting at genome-wide level, and the role of epigenomics in disease biology and epidemiology. This item is printed on demand. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability. N° de réf. du vendeur 9781107697836
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Etat : New. Experts from academia and both the biotechnology and pharmaceutical industries introduce biological, medical and methodological aspects of the emerging field of epigenomics. Editor(s): Appasani, Krishnarao. Num Pages: 574 pages, 100 b/w illus. 24 colour illus. 24 tables. BIC Classification: PSAK1. Category: (P) Professional & Vocational. Dimension: 171 x 244 x 30. Weight in Grams: 926. . 2014. Illustrated. paperback. . . . . N° de réf. du vendeur V9781107697836
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